Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | GFER | P55789 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 14/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | HTR1D | P28221 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | TNFSF11 | O14788 | 1/20 | 0.42 |
| ▸ | TNF | P01375 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30643087 | 0.83 | MAOB (0.64) | NPC1MAPTMAOBUSP2ALDH1A1 | |
| SCHEMBL4974849 | 0.78 | MAOB (0.72) | NPC1RAB9AMAPTSMN1; SMN2MAOB | |
| SCHEMBL30643084 | 0.78 | MAOB (0.72) | NPC1RAB9AMAPTSMN1; SMN2MAOB | |
| SCHEMBL8628828 | 0.77 | ALOX12 (0.50) | NPC1RAB9AMAPTSMN1; SMN2MAOB | |
| SCHEMBL12174817 | 0.72 | PTPN1 (0.67) | NPC1RAB9AMAPTSMN1; SMN2GFER | |
| SCHEMBL31652614 | 0.70 | HTT (0.48) | NPC1RAB9AMAPTSMN1; SMN2MAOB | |
| SCHEMBL21083378 | 0.70 | NPC1 (0.54) | NPC1RAB9ASMN1; SMN2MAOBUSP2 | |
| SCHEMBL29156442 | 0.70 | NPC1 (0.54) | NPC1RAB9AMAPTSMN1; SMN2MAOB | |
| SCHEMBL874939 | 0.70 | ALDH1A1 (0.56) | MAPTSMN1; SMN2MAOBALDH1A1KMT2A | |
| SCHEMBL4381356 | 0.69 | RAB9A (1.00) | NPC1RAB9AMAPTSMN1; SMN2GFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160178597-A1 | Systems and Methods Related to Optical Nanosensors Comprising Photoluminescent Nanostructures | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2016-06-23 | — | — | US | disclosed |