SCHEMBL1785605

SCHEMBL1785605

C=CCOC(C)OC(C)O

nearest known ligand 0.36

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA7 P43166 1/20 0.33
TDP1 Q9NUW8 1/20 0.31
CYP2D6 P10635 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22712843 0.96 CA1 (0.31) CA1CA2CA7
SCHEMBL22712840 0.96 CA1 (0.31) CA1CA2CA7
SCHEMBL5790760 0.85 MEN1 (0.32) CA1CA2TDP1
SCHEMBL25233651 0.82 MEN1 (0.36) CA1CA2CA7TDP1
SCHEMBL272526 0.80
SCHEMBL159503 0.80 LMNA (0.40) CA1CA2CA7TDP1
SCHEMBL25224840 0.79 MEN1 (0.34) CA1CA2CA7TDP1
SCHEMBL483349 0.77 TDP1 (0.31) TDP1
SCHEMBL4710142 0.74 CA1 (0.43) CA1CA2CA7TDP1CYP2D6
SCHEMBL10630125 0.74 CA1 (0.34) CA1CA2CA7TDP1CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3976362-B1 METHOD FOR MAKING OPAQUE COLORED SILICONE HYDROGEL CONTACT LENSES ALCON INC (CH) 2023-06-07 EP claimed
US-11584097-B2 Method for making opaque colored silicone hydrogel contact lenses ALCON INC. (CH) 2023-02-21 US claimed
EP-3976362-A1 METHOD FOR MAKING OPAQUE COLORED SILICONE HYDROGEL CONTACT LENSES Alcon Inc. (CH) 2022-04-06 EP claimed
WO-2020240440-A1 METHOD FOR MAKING OPAQUE COLORED SILICONE HYDROGEL CONTACT LENSES ALCON INC. (CH) 2020-12-03 WO claimed
US-20200376787-A1 METHOD FOR MAKING OPAQUE COLORED SILICONE HYDROGEL CONTACT LENSES ALCON INC. (CH) 2020-12-03 US claimed
EP-3976362-B1 METHOD FOR MAKING OPAQUE COLORED SILICONE HYDROGEL CONTACT LENSES ALCON INC (CH) 2023-06-07 EP disclosed
US-11584097-B2 Method for making opaque colored silicone hydrogel contact lenses ALCON INC. (CH) 2023-02-21 US disclosed
EP-3976362-A1 METHOD FOR MAKING OPAQUE COLORED SILICONE HYDROGEL CONTACT LENSES Alcon Inc. (CH) 2022-04-06 EP disclosed
US-20200376787-A1 METHOD FOR MAKING OPAQUE COLORED SILICONE HYDROGEL CONTACT LENSES ALCON INC. (CH) 2020-12-03 US disclosed
WO-2020240440-A1 METHOD FOR MAKING OPAQUE COLORED SILICONE HYDROGEL CONTACT LENSES ALCON INC. (CH) 2020-12-03 WO disclosed
US-7943380-B2 Leak detection materials and methods BRIGHT SOLUTIONS, INC. (US) 2011-05-17 US disclosed
WO-2005121236-A2 LEAK DETECTION MATERIALS AND METHODS BRIGHT SOLUTIONS, INC. (US) 2005-12-22 WO disclosed
US-20050272844-A1 Leak detection materials and methods KALLEY, TERRENCE 2005-12-08 US disclosed
US-5519154-A ALLYL ALCOHOL, ETHYLENE OXIDE, SULFONATION, ESTERIFICATION HUNTSMAN CORPORATION (US) 1996-05-21 US disclosed
US-4080507-A MAKING TEXTILES OIL AND WATER REPELLENT FMC CORPORATION (US) 1978-03-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11584097-B2 Method for making opaque colored silicone hydrogel contact lenses COIL, CRYAB, CRYAA CA1 1512/4885CA2 3024/4885CA7 758/4885
US-20200376787-A1 METHOD FOR MAKING OPAQUE COLORED SILICONE HYDROGEL CONTACT LENSES COIL, CRYAB, CRYAA CA1 1512/4885CA2 3024/4885CA7 758/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.