Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | STK39 | Q9UEW8 | 3/20 | 0.48 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | PARG | Q86W56 | 1/20 | 0.46 |
| ▸ | PNLIP | P16233 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17845884 | 0.93 | ALDH1A1 (0.53) | ALDH1A1STK39KMT2ANPC1RAB9A | |
| SCHEMBL17859075 | 0.89 | ALDH1A1 (0.47) | ALDH1A1STK39LRRK2KMT2ANPC1 | |
| SCHEMBL17845901 | 0.87 | ALDH1A1 (0.52) | ALDH1A1LRRK2KMT2ANPC1RAB9A | |
| SCHEMBL17845911 | 0.86 | STK39 (0.54) | STK39KMT2ANPC1RAB9AGAA | |
| SCHEMBL17845909 | 0.86 | P2RX1 (0.58) | ALDH1A1STK39LRRK2KMT2ANPC1 | |
| SCHEMBL17845899 | 0.81 | ALDH1A1 (0.51) | ALDH1A1STK39KMT2ANPC1RAB9A | |
| SCHEMBL17845895 | 0.81 | SMN1; SMN2 (0.52) | ALDH1A1LRRK2KMT2ANPC1RAB9A | |
| SCHEMBL7515157 | 0.80 | ALDH1A1 (0.60) | ALDH1A1KMT2ANPC1RAB9AGAA | |
| SCHEMBL17845900 | 0.79 | ALDH1A1 (0.56) | ALDH1A1KMT2ANPC1GAATMPRSS4 | |
| SCHEMBL17858984 | 0.77 | LRRK2 (0.55) | ALDH1A1LRRK2KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016095878-A1 | SUBSTITUTED DERIVATIVE OF OXYPHOSPHORUS ACIDS, ITS USE AND PHARMACEUTICAL PREPARATION CONTAINING IT | UNIVERZITA KARLOVA V PRAZE (CZ) | 2016-06-23 | — | — | WO | disclosed |