SCHEMBL17859642

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4699159	0.85	PSEN1 (0.39)	CES2CES1HTTMAPTMEN1
	SCHEMBL9339071	0.81	MLYCD (0.47)	RECQL
	SCHEMBL27536285	0.77	PSEN1 (0.39)	CES2CES1HTTMAPTMEN1
	SCHEMBL7002940	0.77	FSCN1 (0.49)	ADORA2BCES2CES1HTTMAPT
	SCHEMBL13915059	0.74	S100A4 (0.45)	ADORA2BCES2CES1MAPTMEN1
	SCHEMBL7746135	0.74	PSEN1 (0.38)	CES2CES1HTTMAPTMEN1
	SCHEMBL22187115	0.72	MAPT (0.33)	HTTMAPTMEN1HPGDKMT2A
	SCHEMBL22187113	0.72	MAPT (0.33)	HTTMAPTMEN1HPGDKMT2A
	SCHEMBL6451749	0.72	CYP3A4 (0.46)	ADORA2BCES2CES1HTTMEN1
	SCHEMBL8222920	0.72	DDB1 (0.40)	CES2CES1HTTMAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.