SCHEMBL7746135

SCHEMBL7746135

CC(C)N([C]=O)c1ccc(F)cc1F

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PSEN1 P49768 4/20 0.38
PSEN2 P49810 4/20 0.38
APH1B Q8WW43 4/20 0.38
NCSTN Q92542 4/20 0.38
APH1A Q96BI3 4/20 0.38
PSENEN Q9NZ42 4/20 0.38
CES2 O00748 2/20 0.37
CES1 P23141 2/20 0.37
HTT P42858 1/20 0.37
DDB1 Q16531 1/20 0.36
CRBN Q96SW2 1/20 0.36
MAPT P10636 2/20 0.35
MEN1 O00255 1/20 0.35
HPGD P15428 1/20 0.35
KMT2A Q03164 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
ALDH1A1 P00352 2/20 0.35
TSHR P16473 1/20 0.35
MAPK1 P28482 1/20 0.35
RECQL P46063 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2094176 0.76 DDB1 (0.42) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL27536285 0.75 PSEN1 (0.39) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL17859642 0.74 ADORA2B (0.40) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL8222920 0.73 DDB1 (0.40) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL4699159 0.72 PSEN1 (0.39) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL7746137 0.71 PSEN1 (0.38) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL16914845 0.69 CES2 (0.38) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL9339071 0.69 MLYCD (0.47) RECQL
SCHEMBL13338139 0.68 DDB1 (0.44) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL5716211 0.68 DDB1 (0.44) PSEN1PSEN2APH1BNCSTNAPH1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1402613-A Method for increasing yield of crops BAYER AGROCHEM KK (JP) 2003-03-12 CN disclosed
WO-2001039595-A2 METHOD FOR INCREASING THE YIELD OF CROPS NIHON BAYER AGROCHEM K.K. (DE) 2001-06-07 WO disclosed