Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSEN1 | P49768 | 5/20 | 0.39 |
| ▸ | PSEN2 | P49810 | 5/20 | 0.39 |
| ▸ | APH1B | Q8WW43 | 5/20 | 0.39 |
| ▸ | NCSTN | Q92542 | 5/20 | 0.39 |
| ▸ | APH1A | Q96BI3 | 5/20 | 0.39 |
| ▸ | PSENEN | Q9NZ42 | 5/20 | 0.39 |
| ▸ | CES2 | O00748 | 3/20 | 0.39 |
| ▸ | CES1 | P23141 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.35 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17859642 | 0.85 | ADORA2B (0.40) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL9339071 | 0.80 | MLYCD (0.47) | RECQL | |
| SCHEMBL4696621 | 0.79 | ALDH1A1 (0.41) | CES2CES1HTTMEN1HPGD | |
| SCHEMBL27536285 | 0.76 | PSEN1 (0.39) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL6762131 | 0.75 | ALDH1A1 (0.43) | CES2CES1MAPTMEN1HPGD | |
| SCHEMBL4697782 | 0.73 | TSHR (0.40) | CES2CES1HTTMAPTALDH1A1 | |
| SCHEMBL7746135 | 0.72 | PSEN1 (0.38) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL22187113 | 0.71 | MAPT (0.33) | HTTMAPTMEN1HPGDKMT2A | |
| SCHEMBL22187115 | 0.71 | MAPT (0.33) | HTTMAPTMEN1HPGDKMT2A | |
| SCHEMBL8222920 | 0.71 | DDB1 (0.40) | PSEN1PSEN2APH1BNCSTNAPH1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-10251238-A | — | — | None | — | — | JP | disclosed |
| EP-3677573-B1 | 1-(N,N-DISUBSTITUTED CARBAMOYL) 4-(SUBSTITUTED SULFONYL)TRIAZOLIN-5-ONE DERIVATIVES, 4-(N,N-DISUBSTITUTED CARBAMOYL) 1-(SUBSTITUTED SULFONYL)TRIAZOLIN-5-ONE DERIVATIVES, AND HERBICIDE CONTAINING SAME AS ACTIVE INGREDIENT | HOKKO CHEM IND CO (JP) | 2022-07-27 | — | — | EP | disclosed |
| US-11076595-B2 | 1-(n,n-disubstituted carbamoyl) 4-(substituted sulfonyl)triazolin-5-one derivative, 4-(n,n-disubstituted carbamoyl) 1-(substituted sulfonyl)triazolin-5-one derivative, and herbicide containing said derivative as active ingredient | HOKKO CHEMICAL INDUSTRY CO., LTD. (JP) | 2021-08-03 | — | — | US | disclosed |
| US-20200367499-A1 | 1-(N,N-DISUBSTITUTED CARBAMOYL) 4-(SUBSTITUTED SULFONYL)TRIAZOLIN-5-ONE DERIVATIVE, 4-(N,N-DISUBSTITUTED CARBAMOYL) 1-(SUBSTITUTED SULFONYL)TRIAZOLIN-5-ONE DERIVATIVE, AND HERBICIDE CONTAINING SAID DERIVATIVE AS ACTIVE INGREDIENT | HOKKO CHEMICAL INDUSTRY CO., LTD. (JP) | 2020-11-26 | — | — | US | disclosed |
| EP-3677573-A1 | 1-(N,N-DISUBSTITUTED CARBAMOYL) 4-(SUBSTITUTED SULFONYL)TRIAZOLIN-5-ONE DERIVATIVES, 4-(N,N-DISUBSTITUTED CARBAMOYL) 1-(SUBSTITUTED SULFONYL)TRIAZOLIN-5-ONE DERIVATIVES, AND HERBICIDE CONTAINING SAME AS ACTIVE INGREDIENT | Hokko Chemical Industry Co., Ltd. (JP) | 2020-07-08 | — | — | EP | disclosed |
| CN-111328327-A | 1- (N, N-disubstituted carbamoyl) 4- (substituted sulfonyl) triazolin-5-one derivatives, 4- (N, N-disubstituted carbamoyl) 1- (substituted sulfonyl) triazolin-5-one derivatives and herbicides containing these derivatives as active ingredients | 北兴化学工业株式会社 | 2020-06-23 | — | — | CN | disclosed |
| EP-0974587-B1 | 1-SUBSTITUTED 4-CARBAMOYL-1,2,4-TRIAZOL-5-ONE DERIVATIVES AND HERBICIDE | HOKKO CHEM IND CO (JP) | 2008-04-23 | — | — | EP | disclosed |
| US-6077814-A | LOW PHYTOTOXICITY TO THE CROP PLANTS; SELECTIVE ACTIVITY | HOKKO CHEMICAL INDUSTRY CO., LTD. (JP) | 2000-06-20 | — | — | US | disclosed |
| EP-0974587-A1 | 1-SUBSTITUTED 4-CARBAMOYL-1,2,4-TRIAZOL-5-ONE DERIVATIVES AND HERBICIDE | HOKKO CHEMICAL INDUSTRY CO. LTD. (JP) | 2000-01-26 | — | — | EP | disclosed |
| JP-H10251238-A | TETRAZOLINONE DERIVATIVE AND HERBICIDE | HOKKO CHEM IND CO LTD | 1998-09-22 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11076595-B2 | 1-(n,n-disubstituted carbamoyl) 4-(substituted sulfonyl)triazolin-5-one derivative, 4-(n,n-disubstituted carbamoyl) 1-(substituted sulfonyl)triazolin-5-one derivative, and herbicide containing said derivative as active ingredient | NAT1, SAT1, DDT | PSEN1 2782/4885PSEN2 3820/4885APH1B 646/4885 |
| US-20200367499-A1 | 1-(N,N-DISUBSTITUTED CARBAMOYL) 4-(SUBSTITUTED SULFONYL)TRIAZOLIN-5-ONE DERIVATIVE, 4-(N,N-DISUBSTITUTED CARBAMOYL) 1-(SUBSTITUTED SULFONYL)TRIAZOLIN-5-ONE DERIVATIVE, AND HERBICIDE CONTAINING SAID DERIVATIVE AS ACTIVE INGREDIENT | NAT1, SAT1, NGLY1 | PSEN1 3281/4885PSEN2 4097/4885APH1B 932/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.