Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NMT2 | O60551 | 1/20 | 0.40 |
| ▸ | NMT1 | P30419 | 1/20 | 0.40 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.39 |
| ▸ | NPY1R | P25929 | 3/20 | 0.39 |
| ▸ | NPY4R | P50391 | 3/20 | 0.39 |
| ▸ | FURIN | P09958 | 6/20 | 0.38 |
| ▸ | TLR2 | O60603 | 1/20 | 0.37 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.37 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.37 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.37 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.37 |
| ▸ | SIRT5 | Q9NXA8 | 2/20 | 0.37 |
| ▸ | NPY2R | P49146 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19170793 | 0.89 | C3AR1 (0.44) | NMT2NMT1TLR2C3AR1SIRT6 | |
| SCHEMBL21103049 | 0.82 | SIRT5 (0.38) | NPY5RNPY1RNPY4RC3AR1SIRT6 | |
| SCHEMBL22788819 | 0.81 | NPY5R (0.37) | NPY5RNPY1RNPY4RFURINSIRT6 | |
| SCHEMBL17722924 | 0.81 | NPY5R (0.39) | NPY5RNPY1RNPY4RC3AR1NOD1 | |
| SCHEMBL30524341 | 0.79 | NPY4R (0.48) | NMT2NMT1NPY5RNPY1RNPY4R | |
| SCHEMBL19681473 | 0.79 | NPY5R (0.42) | NMT2NMT1NPY5RNPY1RNPY4R | |
| SCHEMBL25148126 | 0.78 | SIRT5 (0.38) | NMT2NMT1NPY5RNPY1RNPY4R | |
| SCHEMBL22790598 | 0.78 | NPY5R (0.36) | NPY5RNPY1RNPY4RFURINC3AR1 | |
| SCHEMBL23586838 | 0.78 | FURIN (0.39) | NMT2NMT1NPY5RNPY1RNPY4R | |
| SCHEMBL25572196 | 0.78 | NMT2 (0.41) | NMT2NMT1NPY5RNPY1RNPY4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016096610-A1 | ANTIBODY-DRUG CONJUGATES (ADCS) OF KSP INHIBITORS WITH AGLYCOSYLATED ANTI-TWEAKR ANTIBODIES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2016-06-23 | — | — | WO | disclosed |