Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 3/20 | 0.37 |
| ▸ | NPY1R | P25929 | 2/20 | 0.37 |
| ▸ | NPY4R | P50391 | 2/20 | 0.37 |
| ▸ | SIRT5 | Q9NXA8 | 3/20 | 0.36 |
| ▸ | FURIN | P09958 | 8/20 | 0.36 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.34 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.34 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22790598 | 0.89 | NPY5R (0.36) | NPY5RNPY1RNPY4RSIRT5FURIN | |
| SCHEMBL22788736 | 0.88 | FURIN (0.37) | SIRT5FURINSIRT2SIRT6SIRT1 | |
| SCHEMBL21103049 | 0.87 | SIRT5 (0.38) | NPY5RNPY1RNPY4RSIRT5SIRT2 | |
| SCHEMBL20793359 | 0.85 | KISS1R (0.37) | NPY5RNPY1RNPY4RSIRT5SIRT2 | |
| SCHEMBL22708835 | 0.83 | CACNA1B (0.45) | NPY5RNPY1RNPY4RSIRT5 | |
| SCHEMBL17860192 | 0.81 | NMT2 (0.40) | NPY5RNPY1RNPY4RSIRT5FURIN | |
| SCHEMBL12035295 | 0.81 | SIRT5 (0.46) | NPY5RNPY1RNPY4RSIRT5FURIN | |
| SCHEMBL15315075 | 0.79 | C3AR1 (0.38) | SIRT5SIRT6SIRT1 | |
| SCHEMBL10441955 | 0.79 | C3AR1 (0.38) | SIRT5SIRT6SIRT1 | |
| SCHEMBL15691795 | 0.79 | C3AR1 (0.38) | SIRT5SIRT6SIRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020252043-A1 | 5H-PYRROLO[3,2-d]PYRIMIDINE-2,4-DIAMINO COMPOUNDS AND ANTIBODY CONJUGATES THEREOF | SUTRO BIOPHARMA, INC. (US) | 2020-12-17 | — | — | WO | disclosed |