Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 2/20 | 0.36 |
| ▸ | PRKCA | P17252 | 1/20 | 0.34 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.34 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.34 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 3/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
| ▸ | CTSH | P09668 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17860698 | 0.89 | LMNA (0.39) | LMNAMAPTMAPK1ALDH1A1TDP1 | |
| SCHEMBL17882025 | 0.87 | LMNA (0.48) | LMNAMAPTMAPK1ALDH1A1CYP3A4 | |
| SCHEMBL17878557 | 0.84 | LMNA (0.46) | LMNAMAPTMAPK1ALDH1A1CYP3A4 | |
| SCHEMBL29131231 | 0.84 | LMNA (0.65) | LMNAMAPTMAPK1ALDH1A1CYP3A4 | |
| SCHEMBL5962581 | 0.82 | LMNA (0.56) | LMNAMAPTMAPK1ALDH1A1PRKCA | |
| SCHEMBL5962564 | 0.82 | LMNA (0.56) | LMNAMAPTMAPK1ALDH1A1PRKCA | |
| SCHEMBL17860689 | 0.82 | FAAH (0.49) | LMNAMAPTMAPK1ALDH1A1CYP3A4 | |
| SCHEMBL17860691 | 0.82 | LMNA (0.37) | LMNAMAPTMAPK1ALDH1A1 | |
| SCHEMBL28676563 | 0.81 | LMNA (0.65) | LMNAMAPTMAPK1ALDH1A1TSHR | |
| SCHEMBL29577585 | 0.81 | LMNA (0.65) | LMNAMAPTMAPK1ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016100578-A2 | ANTIMICROBIAL POLYMYXINS FOR TREATMENT OF BACTERIAL INFECTIONS | MICURX PHARMACEUTICALS, INC. (US) | 2016-06-23 | — | — | WO | disclosed |