Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA3 | P07451 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 4/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL645070 | 0.86 | CA12 (0.45) | LMNAEPHX2CA12CA1CA2 | |
| SCHEMBL6734553 | 0.84 | LMNA (0.41) | LMNAEPHX2CA12CA1CA2 | |
| SCHEMBL17860717 | 0.83 | LMNA (0.41) | LMNAEPHX2MAPTMAPK1FAAH | |
| SCHEMBL6231000 | 0.82 | LMNA (0.52) | LMNAEPHX2CA12CA1CA2 | |
| SCHEMBL2989645 | 0.82 | ALDH1A1 (0.50) | LMNAEPHX2CA12CA1CA2 | |
| SCHEMBL2980900 | 0.82 | ALDH1A1 (0.50) | LMNAEPHX2CA12CA1CA2 | |
| SCHEMBL10554751 | 0.82 | LMNA (0.57) | LMNAEPHX2CA12CA1CA2 | |
| SCHEMBL1585214 | 0.82 | ALDH1A1 (0.50) | LMNAEPHX2CA12CA1CA2 | |
| SCHEMBL2535166 | 0.81 | LMNA (0.47) | LMNAEPHX2CA12CA1CA2 | |
| SCHEMBL17860689 | 0.80 | FAAH (0.49) | LMNAEPHX2CA1CA2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016100578-A2 | ANTIMICROBIAL POLYMYXINS FOR TREATMENT OF BACTERIAL INFECTIONS | MICURX PHARMACEUTICALS, INC. (US) | 2016-06-23 | — | — | WO | disclosed |