SCHEMBL1786083

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1786652	0.88	KDR (0.45)	KDRKMT2AMEN1NPC1PDGFRB
	SCHEMBL1940427	0.84	FADS1 (0.52)	FADS1KDRKMT2AMEN1BRAF
	SCHEMBL1783816	0.84	KDR (0.46)	KDRKMT2AMEN1NPC1LMNA
	Hydrochloric Acid SCHEMBL1941720	0.83	FADS1 (0.51)	FADS1KDRKMT2AMEN1BRAF
	SCHEMBL1786885	0.82	NPC1 (0.53)	KDRGRM4KMT2AMEN1NPC1
	SCHEMBL4018762	0.82	KDR (0.64)	FADS1KDRKMT2ABRAFAKR1C3
	SCHEMBL1786747	0.81	KDR (0.66)	KDRKMT2AMEN1NPC1LMNA
	SCHEMBL4028532	0.80	KDR (0.55)	FADS1KDRKMT2AMEN1BRAF
	SCHEMBL1786367	0.80	KMT2A (0.52)	KDRKMT2AMEN1NPC1LMNA
	SCHEMBL1789259	0.80	KDR (0.49)	KDRKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.