SCHEMBL1786885

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1786747	0.85	KDR (0.66)	NPC1RAB9AMEN1KMT2AMAPT
	SCHEMBL1786652	0.84	KDR (0.45)	NPC1RAB9AHTTMEN1KMT2A
	SCHEMBL1783816	0.84	KDR (0.46)	NPC1RAB9AHTTMEN1KMT2A
	SCHEMBL1787475	0.84	NPC1 (0.46)	NPC1RAB9AHTTPOLBMEN1
	SCHEMBL1786367	0.82	KMT2A (0.52)	NPC1RAB9AHTTMEN1KMT2A
	SCHEMBL1789259	0.82	KDR (0.49)	KMT2AKDR
	SCHEMBL1787874	0.82	NPC1 (0.51)	NPC1RAB9AALDH1A1CYP3A4CYP1A2
	SCHEMBL1786083	0.82	FADS1 (0.51)	NPC1HTTPOLBMEN1KMT2A
	SCHEMBL4017789	0.82	KDR (0.70)	NPC1RAB9AHTTPABPC1POLB
	SCHEMBL1791423	0.82	KDR (0.51)	KMT2AMAPTCYP3A4KDRSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.