SCHEMBL1786281

SCHEMBL1786281

CCCCC(C)(O)C(C)C=O

nearest known ligand 0.36

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CTSK P43235 1/20 0.36
TSHR P16473 2/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
FDPS P14324 10/20 0.32
GGPS1 O95749 6/20 0.32
ADH1B P00325 1/20 0.31
ADH1C P00326 1/20 0.31
ADH1A P07327 1/20 0.31
ADH4 P08319 1/20 0.31
ADH7 P40394 1/20 0.31
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1784290 0.94 FDPS (0.39) CTSKTSHRSMN1; SMN2FDPSGGPS1
SCHEMBL1785757 0.92 FDPS (0.41) FDPSGGPS1ADH1BADH1CADH1A
SCHEMBL1781949 0.87 FDPS (0.33) CTSKFDPS
SCHEMBL1782307 0.81 GAPDH (0.44) TSHR
SCHEMBL1782308 0.81 GAPDH (0.44) TSHR
SCHEMBL1782458 0.78
SCHEMBL574361 0.75 FDPS (0.33) FDPSGGPS1
SCHEMBL8529254 0.73 FDPS (0.32) TSHRFDPSGGPS1
SCHEMBL27476364 0.72 TSHR (0.35) CTSKTSHRSMN1; SMN2ADH1BADH1C
SCHEMBL1785943 0.72 CTSK (0.34) CTSKTSHRSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8632792-B2 Cooling sensation agent composition and sensory stimulation agent composition TAKASAGO INTERNATIONAL CORPORATION (JP) 2014-01-21 US disclosed
US-20110117147-A1 COOLING SENSATION AGENT COMPOSITION AND SENSORY STIMULATION AGENT COMPOSITION TAKASAGO INTERNATIONAL CORPORATION (JP) 2011-05-19 US disclosed
WO-2009123355-A2 COOLING SENSATION AGENT COMPOSITION AND SENSORY STIMULATION AGENT COMPOSITION TAKASAGO INTERNATIONAL CORPORATION (JP) 2009-10-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110117147-A1 COOLING SENSATION AGENT COMPOSITION AND SENSORY STIMULATION AGENT COMPOSITION TRPA1, HRH1, HRH2 CTSK 4787/4885TSHR 2479/4885SMN1; SMN2 2144/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.