Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | RARA | P10276 | 14/20 | 0.36 |
| ▸ | RARB | P10826 | 14/20 | 0.36 |
| ▸ | RARG | P13631 | 14/20 | 0.36 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19599548 | 0.81 | LMNA (0.37) | RARARARBRARGGPR55CNR2 | |
| SCHEMBL17843543 | 0.81 | LMNA (0.37) | RARARARBRARGGPR55CNR2 | |
| SCHEMBL17864569 | 0.81 | LMNA (0.37) | RARARARBRARGGPR55CNR2 | |
| SCHEMBL17843583 | 0.74 | RARA (0.50) | KDM4ERARARARBRARG | |
| SCHEMBL29396158 | 0.73 | RARA (0.43) | RARARARBRARG | |
| SCHEMBL21562101 | 0.73 | RARA (0.43) | RARARARBRARG | |
| SCHEMBL17988331 | 0.71 | NPC1 (0.40) | KDM4EHSD17B10 | |
| SCHEMBL23691679 | 0.70 | MAPT (0.49) | KDM4ERARARARBRARGGPR55 | |
| SCHEMBL19583279 | 0.70 | RARA (0.36) | RARARARBRARGGPR55CNR2 | |
| SCHEMBL17864618 | 0.69 | RARA (0.37) | KDM4ERARARARBRARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016097004-A1 | BICYCLOHETEROARYL-HETEROARYL-BENZOIC ACID COMPOUNDS AS RETINOIC ACID RECEPTOR BETA (RARβ) AGONISTS | KING'S COLLEGE LONDON (GB) | 2016-06-23 | — | — | WO | disclosed |