SCHEMBL17864825

SCHEMBL17864825

CNC(=O)NCc1cccc(CNC(=O)c2ccccc2)c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC6 Q9UBN7 4/20 0.61
HDAC1 Q13547 2/20 0.61
TP53 P04637 1/20 0.58
HDAC2 Q92769 2/20 0.57
HDAC8 Q9BY41 2/20 0.57
ERCC1 P07992 1/20 0.57
ERCC4 Q92889 1/20 0.57
PPARG P37231 1/20 0.57
NR1H4 Q96RI1 1/20 0.57
HTT P42858 1/20 0.55
KMT2A Q03164 1/20 0.55
ALDH1A1 P00352 1/20 0.55
GAA P10253 1/20 0.55
HSD17B10 Q99714 1/20 0.55
LMNA P02545 1/20 0.54
RAB9A P51151 1/20 0.54
MMP13 P45452 1/20 0.54
APOBEC3A P31941 1/20 0.52
CTDSP1 Q9GZU7 1/20 0.52
APOBEC3G Q9HC16 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11901042 0.89 HDAC6 (0.70) HDAC6HDAC1TP53HDAC2HDAC8
SCHEMBL13853838 0.84 SLC7A5 (0.55) HDAC6TP53HDAC2HDAC8PPARG
SCHEMBL13040551 0.84 HDAC6 (0.60) HDAC6HDAC1HDAC2HDAC8ERCC1
SCHEMBL22047184 0.82 PPARG (0.78) HDAC6HDAC1TP53HDAC2HDAC8
SCHEMBL17863562 0.82 MMP13 (0.61) HDAC6HDAC1HDAC2HDAC8ERCC1
SCHEMBL11205535 0.82 ERCC1 (0.69) HDAC6HDAC1TP53HDAC2HDAC8
SCHEMBL969258 0.82 SMN1; SMN2 (0.67) HDAC6HDAC1TP53KMT2AALDH1A1
SCHEMBL4928443 0.81 CFD (0.74) HDAC6HDAC1HDAC2HDAC8ERCC1
SCHEMBL4977146 0.81 ALDH1A1 (0.65) HDAC6HDAC1HDAC2HDAC8ERCC1
SCHEMBL14365887 0.81 AOC3 (0.63) NR1H4ALDH1A1LMNACFD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9817156-B2 Polarizing plate protective film, polarizing plate and display device FUJIFILM CORPORATION (JP) 2017-11-14 US disclosed
US-20170226317-A1 POLARIZING PLATE PROTECTIVE FILM, POLARIZING PLATE, AND DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2017-08-10 US disclosed
US-9678249-B2 Polarizing plate protective film, polarizing plate and display device FUJIFILM CORPORATION (JP) 2017-06-13 US disclosed
US-20160291213-A1 POLARIZING PLATE PROTECTIVE FILM, POLARIZING PLATE AND DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2016-10-06 US disclosed
US-20160291211-A1 POLARIZING PLATE PROTECTIVE FILM, POLARIZING PLATE AND DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2016-10-06 US disclosed
US-20160291210-A1 POLARIZING PLATE AND DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2016-10-06 US disclosed
US-20160178809-A1 POLARIZING PLATE PROTECTIVE FILM, POLARIZING PLATE, AND DISPLAY FUJIFILM CORPORATION (JP) 2016-06-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170226317-A1 POLARIZING PLATE PROTECTIVE FILM, POLARIZING PLATE, AND DISPLAY DEVICE NBAS, SSB, BIRC5 HDAC6 2856/4885HDAC1 1757/4885TP53 4108/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.