Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 4/20 | 0.42 |
| ▸ | MAOB | P27338 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.39 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17848194 | 0.87 | MAOA (0.42) | MAOAMAOBGAAMAPTHTT | |
| SCHEMBL17848196 | 0.87 | MAOA (0.42) | MAOAMAOBGAAMAPTHTT | |
| SCHEMBL17848427 | 0.85 | MAOB (0.44) | MAOAMAOBGAABCHEMAPT | |
| SCHEMBL17848424 | 0.85 | MAOB (0.44) | MAOAMAOBGAABCHEMAPT | |
| SCHEMBL17864854 | 0.82 | MAOB (0.61) | MAOAMAOBMAPTHTT | |
| SCHEMBL17848312 | 0.79 | RAB9A (0.48) | MAOAMAOBMAPTCYSLTR2CYSLTR1 | |
| SCHEMBL17848314 | 0.79 | RAB9A (0.48) | MAOAMAOBMAPTCYSLTR2CYSLTR1 | |
| SCHEMBL28749229 | 0.74 | MAPT (0.60) | MAOAMAOBGAAMAPTLMNA | |
| SCHEMBL29076154 | 0.74 | MAPT (0.60) | MAOAMAOBGAAMAPTLMNA | |
| SCHEMBL765433 | 0.71 | MAOB (0.61) | MAOAMAOBCYSLTR2CYSLTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016097345-A1 | LABELLED CHROMONE DERIVATIVES | GE HEALTHCARE LIMITED (GB) | 2016-06-23 | — | — | WO | disclosed |