SCHEMBL17864863

SCHEMBL17864863

O=C(NCCNC(=O)OCCOC(=O)Nc1ccccc1)OCCOC(=O)Nc1ccccc1

nearest known ligand 0.69

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 5/20 0.68
RAB9A P51151 5/20 0.68
SMN1; SMN2 Q16637 5/20 0.68
TSHR P16473 1/20 0.68
NPSR1 Q6W5P4 2/20 0.67
RECQL P46063 1/20 0.66
LMNA P02545 4/20 0.65
ALDH1A1 P00352 1/20 0.65
MEN1 O00255 3/20 0.61
KMT2A Q03164 3/20 0.61
TP53 P04637 1/20 0.59
L3MBTL1 Q9Y468 1/20 0.54
MGLL Q99685 1/20 0.54
CHRNA7 P36544 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17346621 0.85 NPC1 (0.72) NPC1RAB9ASMN1; SMN2TSHRNPSR1
SCHEMBL10596423 0.85 NPC1 (0.72) NPC1RAB9ASMN1; SMN2TSHRNPSR1
SCHEMBL12912958 0.84 LMNA (0.60) NPC1RAB9ASMN1; SMN2TSHRNPSR1
SCHEMBL13899392 0.84 NPSR1 (0.60) NPC1RAB9ASMN1; SMN2TSHRNPSR1
SCHEMBL13899407 0.84 NPSR1 (0.60) NPC1RAB9ASMN1; SMN2TSHRNPSR1
SCHEMBL10597471 0.83 RAB9A (0.77) NPC1RAB9ASMN1; SMN2TSHRNPSR1
SCHEMBL17346768 0.83 NPSR1 (0.72) NPC1RAB9ASMN1; SMN2TSHRNPSR1
SCHEMBL11674113 0.82 NPSR1 (0.67) NPC1RAB9ASMN1; SMN2TSHRNPSR1
Phenethyl Phenylcarbamate SCHEMBL1835027 0.82 NPC1 (0.81) NPC1RAB9ASMN1; SMN2TSHRNPSR1
SCHEMBL5623097 0.82 NPC1 (0.68) NPC1RAB9ASMN1; SMN2TSHRNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10457792-B2 Polarizing plate protective film, polarizing plate, and display device FUJIFILM CORPORATION (JP) 2019-10-29 US disclosed
US-10338277-B2 Polarizing plate protective film, polarizing plate, and display FUJIFILM CORPORATION (JP) 2019-07-02 US disclosed
US-10031264-B2 Polarizing plate and display device FUJIFILM CORPORATION (JP) 2018-07-24 US disclosed
US-9817156-B2 Polarizing plate protective film, polarizing plate and display device FUJIFILM CORPORATION (JP) 2017-11-14 US disclosed
US-20170226317-A1 POLARIZING PLATE PROTECTIVE FILM, POLARIZING PLATE, AND DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2017-08-10 US disclosed
US-9678249-B2 Polarizing plate protective film, polarizing plate and display device FUJIFILM CORPORATION (JP) 2017-06-13 US disclosed
US-20160291210-A1 POLARIZING PLATE AND DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2016-10-06 US disclosed
US-20160291211-A1 POLARIZING PLATE PROTECTIVE FILM, POLARIZING PLATE AND DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2016-10-06 US disclosed
US-20160291213-A1 POLARIZING PLATE PROTECTIVE FILM, POLARIZING PLATE AND DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2016-10-06 US disclosed
US-20160178809-A1 POLARIZING PLATE PROTECTIVE FILM, POLARIZING PLATE, AND DISPLAY FUJIFILM CORPORATION (JP) 2016-06-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10457792-B2 Polarizing plate protective film, polarizing plate, and display device NBAS, SSB, GNA15 NPC1 2545/4885RAB9A 1264/4885SMN1; SMN2 2279/4885
US-20170226317-A1 POLARIZING PLATE PROTECTIVE FILM, POLARIZING PLATE, AND DISPLAY DEVICE NBAS, SSB, BIRC5 NPC1 2604/4885RAB9A 1276/4885SMN1; SMN2 2393/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.