SCHEMBL17865334

SCHEMBL17865334

CCCCO/C=C\c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RELA Q04206 1/20 0.47
TDP1 Q9NUW8 1/20 0.44
LTA4H P09960 2/20 0.44
CHRNA7 P36544 6/20 0.43
CHRNA10 Q9GZZ6 5/20 0.43
CHRNA9 Q9UGM1 5/20 0.43
CYP1A2 P05177 2/20 0.42
KDM4E B2RXH2 2/20 0.42
MAPT P10636 1/20 0.42
MEN1 O00255 1/20 0.42
ALDH1A1 P00352 1/20 0.42
TP53 P04637 1/20 0.42
CYP2D6 P10635 1/20 0.42
HPGD P15428 1/20 0.42
ALOX15 P16050 1/20 0.42
KMT2A Q03164 1/20 0.42
HSD17B10 Q99714 1/20 0.42
TRPA1 O75762 1/20 0.42
BCHE P06276 2/20 0.42
CHRNB4 P30926 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL406836 1.00 RELA (0.47) RELATDP1LTA4HCHRNA7CHRNA10
Benzene SCHEMBL28121379 1.00 RELA (0.47) RELATDP1LTA4HCHRNA7CHRNA10
SCHEMBL6055045 1.00 RELA (0.47) RELATDP1LTA4HCHRNA7CHRNA10
SCHEMBL15552968 0.94 LTA4H (0.44) RELATDP1LTA4HCHRNA7CHRNA10
SCHEMBL924663 0.94 LTA4H (0.44) RELATDP1LTA4HCHRNA7CHRNA10
SCHEMBL23244048 0.93 EGFR (0.45) RELATDP1LTA4HCHRNA7CHRNA10
SCHEMBL6313346 0.93 EGFR (0.45) RELATDP1LTA4HCHRNA7CHRNA10
SCHEMBL21596608 0.93 EGFR (0.45) RELATDP1LTA4HCHRNA7CHRNA10
SCHEMBL7540402 0.93 EGFR (0.45) RELATDP1LTA4HCHRNA7CHRNA10
SCHEMBL7541675 0.93 EGFR (0.45) RELATDP1LTA4HCHRNA7CHRNA10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9796647-B2 Method for producing fluorine-containing olefin ASAHI GLASS COMPANY, LIMITED (JP) 2017-10-24 US disclosed
US-20170101360-A1 METHOD FOR PRODUCING FLUORINE-CONTAINING OLEFIN ASAHI GLASS COMPANY, LIMITED (JP) 2017-04-13 US disclosed
US-9598335-B2 Method for producing fluorine-containing olefin ASAHI GLASS COMPANY, LIMITED (JP) 2017-03-21 US disclosed
EP-3042889-A1 METHOD FOR PRODUCING FLUORINE-CONTAINING OLEFIN Asahi Glass Company, Limited (JP) 2016-07-13 EP disclosed
US-20160176791-A1 METHOD FOR PRODUCING FLUORINE-CONTAINING OLEFIN ASAHI GLASS COMPANY, LIMITED (JP) 2016-06-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170101360-A1 METHOD FOR PRODUCING FLUORINE-CONTAINING OLEFIN FOS, CYP2F1, CYP4F11 RELA 3648/4885TDP1 3504/4885LTA4H 3734/4885
US-20160176791-A1 METHOD FOR PRODUCING FLUORINE-CONTAINING OLEFIN FOS, CYP2F1, CYP4F11 RELA 3648/4885TDP1 3504/4885LTA4H 3734/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.