SCHEMBL6313346

SCHEMBL6313346

CCCCCCCO/C=C/c1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
EGFR P00533 1/20 0.45
CHRNA7 P36544 3/20 0.43
CHRNA10 Q9GZZ6 3/20 0.43
CHRNA9 Q9UGM1 3/20 0.43
LTA4H P09960 1/20 0.43
TDP1 Q9NUW8 3/20 0.41
BCHE P06276 3/20 0.41
ACHE P22303 2/20 0.41
LMNA P02545 2/20 0.41
TSHR P16473 1/20 0.41
ALDH1A1 P00352 1/20 0.41
RELA Q04206 1/20 0.41
TP53 P04637 1/20 0.40
MAPT P10636 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
HDAC3 O15379 1/20 0.39
CNR1 P21554 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28131524 1.00 EGFR (0.45) EGFRCHRNA7CHRNA10CHRNA9LTA4H
SCHEMBL6313349 1.00 EGFR (0.45) EGFRCHRNA7CHRNA10CHRNA9LTA4H
SCHEMBL2097271 1.00 EGFR (0.45) EGFRCHRNA7CHRNA10CHRNA9LTA4H
SCHEMBL2706079 1.00 EGFR (0.45) EGFRCHRNA7CHRNA10CHRNA9LTA4H
SCHEMBL7540402 1.00 EGFR (0.45) EGFRCHRNA7CHRNA10CHRNA9LTA4H
SCHEMBL23244048 1.00 EGFR (0.45) EGFRCHRNA7CHRNA10CHRNA9LTA4H
SCHEMBL7538355 1.00 EGFR (0.45) EGFRCHRNA7CHRNA10CHRNA9LTA4H
SCHEMBL7541675 1.00 EGFR (0.45) EGFRCHRNA7CHRNA10CHRNA9LTA4H
SCHEMBL21596608 1.00 EGFR (0.45) EGFRCHRNA7CHRNA10CHRNA9LTA4H
SCHEMBL924663 0.98 LTA4H (0.44) EGFRCHRNA7CHRNA10CHRNA9LTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230257678-A1 ENOL ETHER PROPERFUME FIRMENICH SA (CH) 2023-08-17 US claimed
EP-3746420-B1 ENOL ETHER PROPERFUME FIRMENICH & CIE (CH) 2023-08-16 EP claimed
US-20210115354-A1 ENOL ETHER PROPERFUME FIRMENICH SA (CH) 2021-04-22 US claimed
EP-3746420-A1 ENOL ETHER PROPERFUME Firmenich SA (CH) 2020-12-09 EP claimed
WO-2019243501-A1 ENOL ETHER PROPERFUME FIRMENICH SA (CH) 2019-12-26 WO claimed
US-20230257678-A1 ENOL ETHER PROPERFUME FIRMENICH SA (CH) 2023-08-17 US disclosed
EP-3746420-B1 ENOL ETHER PROPERFUME FIRMENICH & CIE (CH) 2023-08-16 EP disclosed
US-11667869-B2 Enol ether pro perfume FIRMENICH SA (CH) 2023-06-06 US disclosed
US-20210115354-A1 ENOL ETHER PROPERFUME FIRMENICH SA (CH) 2021-04-22 US disclosed
EP-3746420-A1 ENOL ETHER PROPERFUME Firmenich SA (CH) 2020-12-09 EP disclosed
WO-2019243501-A1 ENOL ETHER PROPERFUME FIRMENICH SA (CH) 2019-12-26 WO disclosed
US-6956013-B2 Photo-activated pro-fragrances THE PROCTER & GAMBLE COMPANY (US) 2005-10-18 US disclosed
US-20040087454-A1 Photo-activated pro-fragrances PROCTER & GAMBLE COMPANY, THE 2004-05-06 US disclosed
EP-1377538-A1 PHOTO-ACTIVATED PRO-FRAGRANCES THE PROCTER & GAMBLE COMPANY (US) 2004-01-07 EP disclosed
US-20030004072-A1 Photo-activated pro-fragrances THE PROCTER & GAMBLE COMPANY 2003-01-02 US disclosed
WO-2002083620-A1 PHOTO-ACTIVATED PRO-FRAGRANCES THE PROCTER & GAMBLE COMPANY (US) 2002-10-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11667869-B2 Enol ether pro perfume CYP2E1, ACADM, PEF1 EGFR 3648/4885CHRNA7 2432/4885CHRNA10 3024/4885
US-20230257678-A1 ENOL ETHER PROPERFUME CYP2E1, ADH5, ECI1 EGFR 2703/4885CHRNA7 2343/4885CHRNA10 3157/4885
US-20210115354-A1 ENOL ETHER PROPERFUME CYP2E1, ACADM, ALDH5A1 EGFR 3816/4885CHRNA7 3366/4885CHRNA10 3926/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.