SCHEMBL17865369

SCHEMBL17865369

CC(O)n1ccnc1CO

nearest known ligand 0.34

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
FPR2 P25090 2/20 0.33
FDPS P14324 1/20 0.31
PDE4A P27815 1/20 0.31
PDE4B Q07343 1/20 0.31
PDE4C Q08493 1/20 0.31
PDE4D Q08499 1/20 0.31
OPRK1 P41145 1/20 0.31
KCNH2 Q12809 1/20 0.31
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5654711 0.86 ADORA3 (0.35) FPR2FDPSPDE4APDE4BPDE4C
SCHEMBL18699390 0.82 FPR2 (0.33) FPR2FDPSPDE4APDE4BPDE4C
SCHEMBL5655733 0.81 ADORA2A (0.35) FPR2
SCHEMBL12871185 0.78 L3MBTL1 (0.33) FPR2FDPSPDE4APDE4BPDE4C
SCHEMBL9408485 0.78 FPR2 (0.31) FPR2
SCHEMBL23781954 0.78 PTGS2 (0.32) KCNH2
SCHEMBL28917505 0.77
SCHEMBL21494322 0.75 TLR7 (0.38) KMT2A
SCHEMBL1962600 0.75 TLR7 (0.38) KMT2A
SCHEMBL9408463 0.75 TLR7 (0.38) KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10108129-B2 Member for electrophotography and method of producing the member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2018-10-23 US claimed
US-20160187809-A1 MEMBER FOR ELECTROPHOTOGRAPHY AND METHOD OF PRODUCING THE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2016-06-30 US claimed
EP-3037889-A1 MEMBER FOR ELECTROPHOTOGRAPHY AND METHOD OF PRODUCING THE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS Canon Kabushiki Kaisha (JP) 2016-06-29 EP claimed
EP-3037889-B1 MEMBER FOR ELECTROPHOTOGRAPHY AND METHOD OF PRODUCING THE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS CANON KK (JP) 2023-11-29 EP disclosed
US-10108129-B2 Member for electrophotography and method of producing the member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2018-10-23 US disclosed
US-20160187809-A1 MEMBER FOR ELECTROPHOTOGRAPHY AND METHOD OF PRODUCING THE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2016-06-30 US disclosed
EP-3037889-A1 MEMBER FOR ELECTROPHOTOGRAPHY AND METHOD OF PRODUCING THE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS Canon Kabushiki Kaisha (JP) 2016-06-29 EP disclosed