Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 10/20 | 0.40 |
| ▸ | CES2 | O00748 | 2/20 | 0.39 |
| ▸ | CES1 | P23141 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.35 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17865487 | 0.78 | CES2 (0.40) | MDM2CES2CES1PSMB5 | |
| SCHEMBL17102165 | 0.71 | CASP3 (0.47) | — | |
| SCHEMBL17865486 | 0.70 | CES2 (0.44) | MDM2CES2CES1PSMB5 | |
| SCHEMBL17121664 | 0.69 | CES2 (0.46) | MDM2CES2CES1PSMB5 | |
| SCHEMBL5514599 | 0.68 | NFE2L2 (0.43) | TDP1DPP4DPP9DPP7 | |
| SCHEMBL5514603 | 0.68 | NFE2L2 (0.43) | TDP1DPP4DPP9DPP7 | |
| SCHEMBL22654029 | 0.67 | CYP2C19 (0.49) | L3MBTL1TDP1POLB | |
| SCHEMBL924474 | 0.64 | CYP2C19 (0.46) | L3MBTL1POLB | |
| SCHEMBL8079850 | 0.64 | MEN1 (0.48) | L3MBTL1POLB | |
| SCHEMBL8966854 | 0.64 | MEN1 (0.48) | L3MBTL1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2997008-B1 | PROCESS FOR THE PREPARATION OF KEY INTERMEDIATES OF OMARIGLIPTIN | ITALIANA SINT SPA (IT) | 2016-06-29 | — | — | EP | claimed |