SCHEMBL17865601

SCHEMBL17865601

C=CC(=C)COC(=O)CC

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 8/20 0.41
ALDH1A1 P00352 7/20 0.41
NAAA Q02083 1/20 0.38
HPGD P15428 2/20 0.36
HIF1A Q16665 3/20 0.34
CYP1A2 P05177 1/20 0.34
CYP2C19 P33261 1/20 0.34
BLM P54132 1/20 0.34
WRN Q14191 1/20 0.34
TDP1 Q9NUW8 1/20 0.33
TP53 P04637 2/20 0.31
CYP3A4 P08684 1/20 0.31
HSD17B10 Q99714 1/20 0.31
MGAM O43451 1/20 0.31
GAA P10253 1/20 0.31
SI P14410 1/20 0.31
MGAM2 Q2M2H8 1/20 0.31
SOAT1 P35610 1/20 0.31
THRB P10828 1/20 0.31
PAM P19021 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL504457 0.77
SCHEMBL23093934 0.77 TSHR (0.44) TSHRALDH1A1NAAAHPGDHIF1A
SCHEMBL4675118 0.77 TSHR (0.52) TSHRALDH1A1NAAAHPGDHIF1A
SCHEMBL16713973 0.77 NAAA (0.43) TSHRALDH1A1NAAAHPGDHIF1A
SCHEMBL1332051 0.75
SCHEMBL21385368 0.75 TSHR (0.50) TSHRALDH1A1HPGDHIF1ATP53
SCHEMBL14768554 0.74 TSHR (0.47) TSHRALDH1A1HPGDHIF1ATDP1
SCHEMBL6639977 0.73
SCHEMBL14587464 0.73
SCHEMBL14587492 0.72 CHRNB2 (0.39) TSHRALDH1A1HPGDHIF1ATP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3037405-B1 3-ACYLOXYMETHYL-3-BUTENYL CARBOXYLATE COMPOUND AND METHOD FOR PRODUCING 4-ALKYL-3-METHYLENEBUTYL CARBOXYLATE SHINETSU CHEMICAL CO (JP) 2019-10-30 EP disclosed
US-9499468-B2 3-acyloxymethyl-3-butenyl carboxylate compound and method for producing 4-alkyl-3-methylenebutyl carboxylate SHIN-ETSU CHEMICAL CO., LTD. (JP) 2016-11-22 US disclosed
US-20160185707-A1 3-ACYLOXYMETHYL-3-BUTENYL CARBOXYLATE COMPOUND AND METHOD FOR PRODUCING 4-ALKYL-3-METHYLENEBUTYL CARBOXYLATE SHIN-ETSU CHEMICAL CO., LTD. (JP) 2016-06-30 US disclosed
EP-3037405-A1 3-ACYLOXYMETHYL-3-BUTENYL CARBOXYLATE COMPOUND AND METHOD FOR PRODUCING 4-ALKYL-3-METHYLENEBUTYL CARBOXYLATE Shin-Etsu Chemical Co., Ltd. (JP) 2016-06-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160185707-A1 3-ACYLOXYMETHYL-3-BUTENYL CARBOXYLATE COMPOUND AND METHOD FOR PRODUCING 4-ALKYL-3-METHYLENEBUTYL CARBOXYLATE HACL2, MBOAT7, MCCC2 TSHR 3103/4885ALDH1A1 710/4885NAAA 251/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.