Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.51 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | PROKR1 | Q8TCW9 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.42 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.42 |
| ▸ | VNN1 | O95497 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17865885 | 0.86 | TP53 (0.45) | TP53AKR1C3NPC1HCRTR1HCRTR2 | |
| SCHEMBL17865891 | 0.78 | AKR1C3 (0.43) | TP53AKR1C3NPC1VNN1NAMPT | |
| SCHEMBL27249755 | 0.74 | HSD11B1 (0.54) | TP53AKR1C3HCRTR1HCRTR2NAMPT | |
| SCHEMBL17850446 | 0.74 | NAMPT (0.58) | TP53AKR1C3NPC1NAMPT | |
| SCHEMBL15323487 | 0.73 | TP53 (0.35) | TP53AKR1C3NPC1HCRTR1HCRTR2 | |
| SCHEMBL7401006 | 0.70 | NAMPT (0.64) | TP53AKR1C3NPC1HCRTR1HCRTR2 | |
| SCHEMBL21973846 | 0.70 | TP53 (0.54) | TP53AKR1C3HCRTR1HCRTR2NAMPT | |
| SCHEMBL13290439 | 0.70 | AKR1C3 (0.46) | TP53AKR1C3NPC1NAMPT | |
| SCHEMBL19277071 | 0.70 | AKR1C3 (0.46) | TP53AKR1C3NPC1NAMPT | |
| SCHEMBL22968141 | 0.70 | AKR1C3 (0.46) | TP53AKR1C3NPC1NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2836489-B1 | N-ACYL-2-(CYCLO) ALKYLPYRROLIDINES AND PIPERIDINES USEFUL AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2016-06-29 | — | — | EP | claimed |
| EP-2836489-B1 | N-ACYL-2-(CYCLO) ALKYLPYRROLIDINES AND PIPERIDINES USEFUL AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2016-06-29 | — | — | EP | disclosed |