Imidazole

Imidazole

SCHEMBL17867609

CC(C)(C)OC(=O)n1ccnc1.c1c[nH]cn1

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.37
FKBP5 Q13451 1/20 0.37
GPR119 Q8TDV5 8/20 0.36
L3MBTL1 Q9Y468 1/20 0.32
CYP24A1 Q07973 2/20 0.32
TBXAS1 P24557 1/20 0.31
CYP17A1 P05093 1/20 0.31
USP2 O75604 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL217823 0.86 GPR119 (0.42) GPR119L3MBTL1CYP24A1TBXAS1CYP17A1
Imidazole SCHEMBL396144 0.76 MAPK1 (0.43) GPR119USP2SMN1; SMN2
Imidazole SCHEMBL28418796 0.75 ALDH1A1 (0.48) ALDH1A1FKBP5
Imidazole SCHEMBL7859328 0.75 ALDH1A1 (0.48) ALDH1A1FKBP5
Imidazole SCHEMBL9377131 0.72 ALDH1A1 (0.48) ALDH1A1FKBP5
SCHEMBL10359587 0.71 TBXAS1 (0.36) ALDH1A1GPR119CYP24A1TBXAS1CYP17A1
SCHEMBL14158754 0.71 GPR119 (0.35) ALDH1A1GPR119L3MBTL1CYP24A1TBXAS1
SCHEMBL1199386 0.71 AHR (0.36) ALDH1A1GPR119CYP24A1TBXAS1CYP17A1
SCHEMBL6899758 0.71 L3MBTL1 (0.43) GPR119L3MBTL1CYP24A1CYP17A1
SCHEMBL2262506 0.71 ALDH1A1 (0.52) ALDH1A1GPR119USP2SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9690196-B2 Photoimageable compositions containing thermal base generators PROMERUS, LLC (US) 2017-06-27 US disclosed
US-20160187775-A1 PHOTOIMAGEABLE COMPOSITIONS CONTAINING THERMAL BASE GENERATORS SUMITOMO BAKELITE CO., LTD. (JP) 2016-06-30 US disclosed