SCHEMBL17868786

SCHEMBL17868786

C=C(C)C(=O)OCC(C)CC(O)Cc1cccc(C(=O)O)c1C(=O)O

nearest known ligand 0.38

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.38
POLB P06746 1/20 0.32
APEX1 P27695 1/20 0.32
HTT P42858 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
FOLH1 Q04609 2/20 0.31
SLC37A4 O43826 1/20 0.30
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL587392 0.84 TSHR (0.38) TSHRFOLH1ALDH1A1
SCHEMBL472203 0.83 POLB (0.38) TSHRPOLBAPEX1HTTTDP1
SCHEMBL19611833 0.78 FOLH1 (0.40) TSHRPOLBAPEX1HTTTDP1
SCHEMBL244340 0.77 PRKCG (0.36) TSHRTDP1FOLH1SLC37A4ALDH1A1
SCHEMBL14764725 0.77 PRKCG (0.33) FOLH1SLC37A4ALDH1A1
SCHEMBL7794262 0.77 TSHR (0.38) TSHRPOLBAPEX1HTTTDP1
SCHEMBL15901933 0.75 POLB (0.33) POLBAPEX1HTTTDP1
SCHEMBL815211 0.75 TDP1 (0.38) TSHRPOLBAPEX1HTTTDP1
SCHEMBL29859865 0.75 POLB (0.36) TSHRPOLBAPEX1HTTTDP1
SCHEMBL36344 0.74 POLB (0.43) TSHRPOLBAPEX1HTTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3050555-A1 ARTIFICIAL NAIL COMPOSITION, ARTIFICIAL NAIL, ARTIFICIAL NAIL FORMING METHOD, AND NAIL ART KIT Fujifilm Corporation (JP) 2016-08-03 EP disclosed
US-20160184213-A1 ARTIFICIAL NAIL COMPOSITION, ARTIFICIAL NAIL, ARTIFICIAL NAIL FORMING METHOD, AND NAIL ART KIT FUJIFILM CORPORATION (JP) 2016-06-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160184213-A1 ARTIFICIAL NAIL COMPOSITION, ARTIFICIAL NAIL, ARTIFICIAL NAIL FORMING METHOD, AND NAIL ART KIT PIK3C3, POLR1C, PRKDC TSHR 2386/4885POLB 239/4885APEX1 2685/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.