Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6363482 | 0.81 | TSHR (0.36) | TSHR | |
| SCHEMBL28711621 | 0.81 | POLB (0.36) | POLBAPEX1HTTTDP1 | |
| SCHEMBL23140729 | 0.79 | TSHR (0.39) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL815209 | 0.79 | POLB (0.38) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL815210 | 0.79 | POLB (0.38) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL10414804 | 0.78 | ALDH1A1 (0.31) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL17868786 | 0.77 | TSHR (0.38) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL11216168 | 0.77 | ADRB2 (0.35) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL472203 | 0.75 | POLB (0.38) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL2237265 | 0.74 | POLB (0.42) | TSHRPOLBAPEX1HTTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0710475-B1 | High refractive index and/or radio-opaque resins systems | ABONETICS LTD (GB) | 2001-11-21 | — | — | EP | disclosed |
| US-5679710-A | DENTAL COMPOSITES | LONDON HOSPITAL MEDICAL COLLEGE (GB) | 1997-10-21 | — | — | US | disclosed |
| EP-0710475-A1 | High refractive index and/or radio-opaque resins systems | THE LONDON HOSPITAL MEDICAL COLLEGE (GB) | 1996-05-08 | — | — | EP | disclosed |