Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | ACR | P10323 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5475298 | 1.00 | TP53 (0.38) | TP53CA12CA1CA2CA9 | |
| SCHEMBL7856507 | 0.80 | ALDH1A1 (0.41) | ACRKMT2AALDH1A1 | |
| SCHEMBL8928181 | 0.80 | REN (0.41) | ACRKMT2AATMALDH1A1 | |
| SCHEMBL2886330 | 0.80 | CA1 (0.56) | CA12CA1CA2CA9TDP1 | |
| SCHEMBL4572780 | 0.80 | CA1 (0.39) | TP53CA12CA1CA2CA9 | |
| SCHEMBL10991842 | 0.80 | CA1 (0.39) | TP53CA12CA1CA2CA9 | |
| Hydrochloric Acid SCHEMBL11601843 | 0.78 | CA1 (0.54) | CA12CA1CA2CA9TDP1 | |
| SCHEMBL6061789 | 0.78 | CA12 (0.37) | TP53CA12CA1CA2CA9 | |
| Methacrylic Acid SCHEMBL6674623 | 0.77 | ACR (0.33) | ACR | |
| SCHEMBL6998369 | 0.77 | LMNA (0.53) | CA12CA9TSHRKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3237403-A1 | NOVEL HETEROCYCLIC COMPOUNDS AND THE USE THEREOF IN MEDICINE AND IN COSMETICS | Galderma Research & Development (FR) | 2017-11-01 | — | — | EP | disclosed |
| WO-2016102882-A1 | NOVEL HETEROCYCLIC COMPOUNDS AND THE USE THEREOF IN MEDICINE AND IN COSMETICS | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2016-06-30 | — | — | WO | disclosed |