Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 6/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | THRA | P10827 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | RXRB | P28702 | 1/20 | 0.35 |
| ▸ | RXRG | P48443 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6473993 | 0.85 | NPC1 (0.39) | NPC1RAB9AALDH1A1TSHRTRPV1 | |
| SCHEMBL6473995 | 0.85 | NPC1 (0.56) | NPC1RAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL24534295 | 0.81 | ALDH1A1 (0.43) | NPC1RAB9AALDH1A1TSHRMEN1 | |
| SCHEMBL17873261 | 0.77 | RXFP1 (0.41) | NPC1RAB9ALMNAPOLB | |
| SCHEMBL19305874 | 0.77 | ALDH1A1 (0.60) | ALDH1A1TSHRTRPV1MEN1KMT2A | |
| SCHEMBL9381352 | 0.75 | KDM4E (0.43) | NPC1RAB9AALDH1A1TSHRMEN1 | |
| SCHEMBL8306884 | 0.74 | KDM4E (0.33) | NPC1RAB9AALDH1A1KDM4EPOLB | |
| SCHEMBL6627142 | 0.74 | ALDH1A1 (0.65) | ALDH1A1TSHRMEN1KMT2ALMNA | |
| SCHEMBL17873244 | 0.72 | POLB (0.35) | NPC1RAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL1156914 | 0.71 | NPC1 (0.74) | NPC1RAB9AALDH1A1TSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3237410-B1 | AZOLINE COMPOUNDS SUBSTITUTED BY A CONDENSED RING SYSTEM | BASF SE (DE) | 2020-12-16 | — | — | EP | disclosed |
| US-10273231-B2 | Azoline compounds substituted by a condensed ring system | BASF SE (DE) | 2019-04-30 | — | — | US | disclosed |
| US-20190040050-A1 | AZOLINE COMPOUNDS SUBSTITUTED BY A CONDENSED RING SYSTEM | BASF SE (DE) | 2019-02-07 | — | — | US | disclosed |
| US-10093662-B2 | Azoline compounds substituted by a condensed ring system | BASF SE (DE) | 2018-10-09 | — | — | US | disclosed |
| US-20180002323-A1 | AZOLINE COMPOUNDS SUBSTITUTED BY A CONDENSED RING SYSTEM | BASF SE (DE) | 2018-01-04 | — | — | US | disclosed |
| EP-3237410-A1 | AZOLINE COMPOUNDS SUBSTITUTED BY A CONDENSED RING SYSTEM | BASF SE (DE) | 2017-11-01 | — | — | EP | disclosed |
| WO-2016102482-A1 | AZOLINE COMPOUNDS SUBSTITUTED BY A CONDENSED RING SYSTEM | BASF SE (DE) | 2016-06-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190040050-A1 | AZOLINE COMPOUNDS SUBSTITUTED BY A CONDENSED RING SYSTEM | CUL5, CUL1, CUL3 | NPC1 2166/4885RAB9A 2401/4885ALDH1A1 1791/4885 |
| US-20180002323-A1 | AZOLINE COMPOUNDS SUBSTITUTED BY A CONDENSED RING SYSTEM | CUL1, CRY1, CUL5 | NPC1 1348/4885RAB9A 1657/4885ALDH1A1 1313/4885 |
| US-10093662-B2 | Azoline compounds substituted by a condensed ring system | CUL1, CRY1, CUL5 | NPC1 1348/4885RAB9A 1657/4885ALDH1A1 1313/4885 |
| US-10273231-B2 | Azoline compounds substituted by a condensed ring system | CUL5, CUL1, CUL3 | NPC1 2166/4885RAB9A 2401/4885ALDH1A1 1791/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.