Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 6/20 | 0.33 |
| ▸ | NPC1 | O15118 | 4/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CASP6 | P55212 | 1/20 | 0.31 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17873258 | 0.77 | AAK1 (0.40) | HTTRXFP1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL31182208 | 0.77 | AAK1 (0.40) | HTTRXFP1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL21955179 | 0.74 | CYP2A13 (0.34) | — | |
| SCHEMBL30915590 | 0.74 | CYP2A13 (0.34) | — | |
| SCHEMBL17873243 | 0.72 | NPC1 (0.40) | POLBRAB9ANPC1ALDH1A1KMT2A | |
| SCHEMBL1978079 | 0.66 | RXFP1 (0.71) | HTTRXFP1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL30567319 | 0.66 | RXFP1 (0.51) | POLBHPGDRXFP1RAB9ANPC1 | |
| SCHEMBL6674584 | 0.66 | RXFP1 (0.51) | POLBHPGDRXFP1RAB9ANPC1 | |
| SCHEMBL29250418 | 0.64 | CYP1A2 (0.38) | ALDH1A1KMT2AMEN1CYP1A2 | |
| SCHEMBL15414259 | 0.64 | GPR35 (0.37) | POLBHTTRXFP1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3237410-B1 | AZOLINE COMPOUNDS SUBSTITUTED BY A CONDENSED RING SYSTEM | BASF SE (DE) | 2020-12-16 | — | — | EP | disclosed |
| US-10273231-B2 | Azoline compounds substituted by a condensed ring system | BASF SE (DE) | 2019-04-30 | — | — | US | disclosed |
| US-20190040050-A1 | AZOLINE COMPOUNDS SUBSTITUTED BY A CONDENSED RING SYSTEM | BASF SE (DE) | 2019-02-07 | — | — | US | disclosed |
| US-10093662-B2 | Azoline compounds substituted by a condensed ring system | BASF SE (DE) | 2018-10-09 | — | — | US | disclosed |
| US-20180002323-A1 | AZOLINE COMPOUNDS SUBSTITUTED BY A CONDENSED RING SYSTEM | BASF SE (DE) | 2018-01-04 | — | — | US | disclosed |
| EP-3237410-A1 | AZOLINE COMPOUNDS SUBSTITUTED BY A CONDENSED RING SYSTEM | BASF SE (DE) | 2017-11-01 | — | — | EP | disclosed |
| WO-2016102482-A1 | AZOLINE COMPOUNDS SUBSTITUTED BY A CONDENSED RING SYSTEM | BASF SE (DE) | 2016-06-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190040050-A1 | AZOLINE COMPOUNDS SUBSTITUTED BY A CONDENSED RING SYSTEM | CUL5, CUL1, CUL3 | POLB 2758/4885HPGD 3497/4885HTT 1021/4885 |
| US-20180002323-A1 | AZOLINE COMPOUNDS SUBSTITUTED BY A CONDENSED RING SYSTEM | CUL1, CRY1, CUL5 | POLB 3106/4885HPGD 3189/4885HTT 1384/4885 |
| US-10093662-B2 | Azoline compounds substituted by a condensed ring system | CUL1, CRY1, CUL5 | POLB 3106/4885HPGD 3189/4885HTT 1384/4885 |
| US-10273231-B2 | Azoline compounds substituted by a condensed ring system | CUL5, CUL1, CUL3 | POLB 2758/4885HPGD 3497/4885HTT 1021/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.