Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | HTR5A | P47898 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18397703 | 0.77 | CFTR (0.33) | DRD2DRD4DRD3HTR5ACYP1A2 | |
| SCHEMBL38658847 | 0.76 | CA1 (0.42) | CYP1A2KDM4EALDH1A1CA12CA1 | |
| SCHEMBL18397725 | 0.73 | SLC6A3 (0.40) | CYP1A2KDM4EALDH1A1CA12CA1 | |
| SCHEMBL11630296 | 0.73 | DRD2 (0.57) | DRD2DRD4DRD3HTR5AKDM4E | |
| SCHEMBL17873248 | 0.72 | CA1 (0.39) | CYP1A2KDM4EALDH1A1CA12CA1 | |
| SCHEMBL22084664 | 0.72 | KDM4E (0.37) | KDM4EALDH1A1CA12CA1CA2 | |
| SCHEMBL10164852 | 0.72 | PTGER4 (0.43) | DRD2DRD4DRD3HTR5AKDM4E | |
| SCHEMBL22032149 | 0.72 | KDM4E (0.37) | KDM4EALDH1A1CA12CA1CA2 | |
| SCHEMBL22032138 | 0.70 | KDM4E (0.39) | KDM4EALDH1A1CA12CA1CA2 | |
| SCHEMBL18397712 | 0.70 | KDM4E (0.50) | KDM4EALDH1A1CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180215740-A1 | PARA-SUBSTITUTED INDANYL AND TETRALINYL DERIVATIVES | BASF SE (DE) | 2018-08-02 | — | — | US | disclosed |
| EP-3325439-A1 | PARA-SUBSTITUTED INDANYL AND TETRALINYL DERIVATIVES | BASF SE (DE) | 2018-05-30 | — | — | EP | disclosed |
| WO-2017012938-A1 | PARA-SUBSTITUTED INDANYL AND TETRALINYL DERIVATIVES | BASF SE (DE) | 2017-01-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180215740-A1 | PARA-SUBSTITUTED INDANYL AND TETRALINYL DERIVATIVES | CYP4F2, INTS6, CYP11B2 | DRD2 2858/4885DRD4 2590/4885DRD3 3009/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.