SCHEMBL1787407

SCHEMBL1787407

CCOC(=O)Oc1c(F)cc(F)cc1F

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.43
SOAT1 P35610 1/20 0.40
CUL4A Q13619 3/20 0.40
MAPT P10636 3/20 0.39
POLB P06746 1/20 0.39
RAB9A P51151 1/20 0.39
TSHR P16473 1/20 0.38
KMT2A Q03164 3/20 0.37
MEN1 O00255 1/20 0.37
LMNA P02545 1/20 0.37
CYP1A2 P05177 1/20 0.37
CYP2C9 P11712 1/20 0.37
CYP2C19 P33261 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
GAA P10253 2/20 0.36
TDP1 Q9NUW8 2/20 0.36
CA12 O43570 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA7 P43166 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19543215 0.89 ALDH1A1 (0.43) ALDH1A1SOAT1CUL4AMAPTKMT2A
SCHEMBL1790431 0.83 ESR1 (0.44) ALDH1A1TSHRTDP1
SCHEMBL5272075 0.82 CES2 (0.43) KMT2AGAACA12CA1CA9
SCHEMBL27215072 0.81 NLRP3 (0.46) ALDH1A1SOAT1POLBRAB9ATSHR
SCHEMBL1791834 0.81 TSHR (0.39) ALDH1A1MAPTTSHRKMT2AMEN1
SCHEMBL1791270 0.79 CYP4F2 (0.46) ALDH1A1SOAT1CUL4AMAPTPOLB
SCHEMBL28443488 0.79 CES2 (0.38) POLBRAB9AKMT2AGAAKDM4E
SCHEMBL27502208 0.78 MAPT (0.35) ALDH1A1MAPTPOLBRAB9ATSHR
SCHEMBL1401567 0.78 ALDH1A1 (0.52) ALDH1A1SOAT1CUL4AMAPTRAB9A
SCHEMBL810613 0.77 FAAH (0.46) ALDH1A1MAPTPOLBRAB9ATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2249426-B1 NONAQUEOUS ELECTROLYTE SOLUTION AND NONAQUEOUS ELECTROLYTE BATTERY MITSUBISHI CHEM CORP (JP) 2019-07-10 EP disclosed
US-9083058-B2 Nonaqueous electrolytic solution and nonaqueous-electrolyte battery MITSUBISHI CHEMICAL CORPORATION (JP) 2015-07-14 US disclosed
US-8916298-B2 Nonaqueous electrolytic solution and nonaqueous-electrolyte battery MITSUBISHI CHEMICAL CORPORATION (JP) 2014-12-23 US disclosed
US-8889302-B2 Nonaqueous electrolytic solution and nonaqueous-electrolyte battery MITSUBISHI CHEMICAL CORPORATION (JP) 2014-11-18 US disclosed
US-8846254-B2 2014-09-30 US disclosed
US-20140134481-A1 NONAQUEOUS ELECTROLYTIC SOLUTION AND NONAQUEOUS-ELECTROLYTE BATTERY MITSUBISHI CHEMICAL CORPORATION (JP) 2014-05-15 US disclosed
US-20120308883-A1 NONAQUEOUS ELECTROLYTIC SOLUTION AND NONAQUEOUS-ELECTROLYTE BATTERY MITSUBISHI CHEMICAL CORPORATION (JP) 2012-12-06 US disclosed
US-20120219854-A1 NONAQUEOUS ELECTROLYTIC SOLUTION AND NONAQUEOUS-ELECTROLYTE BATTERY MITSUBISHI CHEMICAL CORPORATION (JP) 2012-08-30 US disclosed
US-20110123871-A1 NONAQUEOUS ELECTROLYTIC SOLUTION AND NONAQUEOUS-ELECTROLYTE BATTERY MITSUBISHI CHEMCIAL (JP) 2011-05-26 US disclosed
EP-2249426-A1 NONAQUEOUS ELECTROLYTE SOLUTION AND NONAQUEOUS ELECTROLYTE BATTERY Mitsubishi Chemical Corporation (JP) 2010-11-10 EP disclosed