Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMD11 | O00231 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | RNF168 | Q8IYW5 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.32 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.31 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.31 |
| ▸ | PSMB1 | P20618 | 5/20 | 0.31 |
| ▸ | PSMB5 | P28074 | 5/20 | 0.31 |
| ▸ | PSMB2 | P49721 | 5/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10025880 | 0.80 | CA12 (0.56) | PSMD11CA12CA1CA2CA9 | |
| SCHEMBL10025884 | 0.72 | CA12 (0.58) | PSMD11CA12CA1CA2CA9 | |
| SCHEMBL10025883 | 0.69 | CA12 (0.59) | CA12CA1CA2CA9RNF168 | |
| SCHEMBL13845558 | 0.67 | TPSAB1 (0.48) | KMT2ALMNAHDAC3HDAC4HDAC1 | |
| SCHEMBL10025882 | 0.67 | GAA (0.47) | KMT2ALMNAHDAC1HDAC6ALDH1A1 | |
| SCHEMBL11896724 | 0.66 | CA12 (0.38) | PSMD11CA12CA1CA2CA9 | |
| SCHEMBL2749274 | 0.64 | PIN1 (0.56) | LMNA | |
| SCHEMBL11896715 | 0.63 | CA12 (0.59) | CA12CA1CA2CA9RNF168 | |
| SCHEMBL18573951 | 0.61 | SMN1; SMN2 (0.47) | KMT2AHDAC1HDAC6MEN1ALDH1A1 | |
| SCHEMBL19526079 | 0.61 | HLCS (0.38) | KMT2AMEN1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1874738-B1 | PYRIMIDINES REACTING WITH O6-ALKYLGUANINE-DNA ALKYLTRANSFERASE | COVALYS BIOSCIENCES AG (CH) | 2016-06-29 | — | — | EP | disclosed |