SCHEMBL17875588

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL13309242	0.88	MAPT (0.47)	MAPTSMN1; SMN2GAAALDH1A1MCOLN3
	SCHEMBL22133009	0.85	MAPT (0.42)	MAPTSMN1; SMN2GAAALDH1A1HTT
	SCHEMBL17875594	0.82	MAPT (0.43)	MAPTSMN1; SMN2GAAALDH1A1HTT
	SCHEMBL17875596	0.79	MAPT (0.50)	MAPTSMN1; SMN2GAAALDH1A1LMNA
	SCHEMBL17703330	0.78	MAPT (0.39)	MAPTSMN1; SMN2GAAALDH1A1MEN1
	SCHEMBL22100181	0.77	MAPT (0.39)	MAPTSMN1; SMN2GAAALDH1A1HTT
	SCHEMBL15297298	0.77	VDR (0.56)	MAPTSMN1; SMN2GAAALDH1A1MEN1
	SCHEMBL17875590	0.75	MAPT (0.69)	MAPTSMN1; SMN2GAAALDH1A1HTT
	SCHEMBL17703324	0.72	VDR (0.45)	MAPTSMN1; SMN2GAAALDH1A1HTT
	SCHEMBL15307675	0.72	VDR (0.45)	MAPTPOLBMEN1KMT2AL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.