SCHEMBL17875596

SCHEMBL17875596

Cc1cc(C)cc(N2COc3cc(C)ccc3C2)c1

nearest known ligand 0.50

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.50
ALDH1A1 P00352 1/20 0.50
VDR P11473 1/20 0.43
GAA P10253 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
ACLY P53396 1/20 0.34
LMNA P02545 1/20 0.32
KCNQ2 O43526 1/20 0.32
NPC1 O15118 1/20 0.32
RAB9A P51151 1/20 0.32
TERT O14746 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15297298 0.88 VDR (0.56) MAPTALDH1A1VDRGAASMN1; SMN2
SCHEMBL19501007 0.84 MAPT (0.64) MAPTALDH1A1VDRGAASMN1; SMN2
SCHEMBL17875595 0.84 MAPT (0.44) MAPTALDH1A1VDRGAASMN1; SMN2
SCHEMBL17703330 0.82 MAPT (0.39) MAPTALDH1A1VDRGAASMN1; SMN2
SCHEMBL17875588 0.79 MAPT (0.46) MAPTALDH1A1VDRGAASMN1; SMN2
SCHEMBL15307675 0.79 VDR (0.45) MAPTVDRNPC1
SCHEMBL17703324 0.79 VDR (0.45) MAPTALDH1A1VDRGAASMN1; SMN2
SCHEMBL17875589 0.78 VDR (0.44) MAPTALDH1A1VDRGAASMN1; SMN2
SCHEMBL22133009 0.77 MAPT (0.42) MAPTALDH1A1VDRGAASMN1; SMN2
SCHEMBL15297330 0.77 VDR (0.52) MAPTALDH1A1VDRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230133556-A1 BENZOXAZINES AND COMPOSITIONS CONTAINING THE SAME CYTEC INDUSTRIES INC 2023-05-04 US disclosed
US-20230133556-A1 BENZOXAZINES AND COMPOSITIONS CONTAINING THE SAME CYTEC INDUSTRIES INC 2023-05-04 US disclosed
US-11566106-B2 Composite materials containing benzoxazines and method for making the same CYTEC INDUSTRIES INC. (US) 2023-01-31 US disclosed
US-20200291179-A1 COMPOSITE MATERIALS CONTAINING BENZOXAZINES AND METHOD FOR MAKING THE SAME CYTEC INDUSTRIES INC. (US) 2020-09-17 US disclosed
EP-3240829-B1 BENZOXAZINES AND COMPOSITIONS CONTAINING THE SAME CYTEC IND INC (US) 2019-08-21 EP disclosed
WO-2016109399-A1 BENZOXAZINES AND COMPOSITIONS CONTAINING THE SAME CYTEC INDUSTRIES INC. (US) 2016-07-07 WO disclosed
US-20160185908-A1 BENZOXAZINES AND COMPOSITIONS CONTAINING THE SAME CYTEC INDUSTRIES INC. (US) 2016-06-30 US disclosed
US-20160185908-A1 BENZOXAZINES AND COMPOSITIONS CONTAINING THE SAME CYTEC INDUSTRIES INC. (US) 2016-06-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200291179-A1 COMPOSITE MATERIALS CONTAINING BENZOXAZINES AND METHOD FOR MAKING THE SAME F12, COL1A1, BRIX1 MAPT 2756/4885ALDH1A1 1216/4885VDR 1918/4885
US-11566106-B2 Composite materials containing benzoxazines and method for making the same F12, COL1A1, BRIX1 MAPT 2756/4885ALDH1A1 1216/4885VDR 1918/4885
US-20230133556-A1 BENZOXAZINES AND COMPOSITIONS CONTAINING THE SAME F12, BRIX1, COL1A1 MAPT 2194/4885ALDH1A1 1160/4885VDR 1606/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.