SCHEMBL17875847

SCHEMBL17875847

c1ccc2c(c1)oc1cccc(-c3ccc4c(c3)COCc3ccc(-c5cccc6oc7ccccc7c56)cc3-4)c12

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSP90AA1 P07900 1/20 0.38
ALOX5 P09917 2/20 0.37
BACE1 P56817 1/20 0.34
PRKDC P78527 1/20 0.33
NQO1 P15559 1/20 0.33
MAOA P21397 2/20 0.31
PLA2G2A P14555 2/20 0.31
PLA2G4A P47712 2/20 0.31
KDM4E B2RXH2 1/20 0.30
ALDH1A1 P00352 1/20 0.30
GLA P06280 1/20 0.30
CYP3A4 P08684 1/20 0.30
MAPT P10636 1/20 0.30
HPGD P15428 1/20 0.30
PGAM1 P18669 1/20 0.30
CASP1 P29466 1/20 0.30
CASP7 P55210 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
HSD17B10 Q99714 1/20 0.30
CDC14B O60729 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17875908 0.95 ALOX5 (0.40) HSP90AA1ALOX5BACE1PRKDCNQO1
SCHEMBL17875839 0.94 ALOX5 (0.36) HSP90AA1ALOX5BACE1PRKDCNQO1
SCHEMBL17875848 0.94 ALOX5 (0.36) HSP90AA1ALOX5BACE1PRKDCNQO1
SCHEMBL17875834 0.94 PRKDC (0.39) HSP90AA1ALOX5BACE1PRKDCNQO1
SCHEMBL17875845 0.94 PRKDC (0.39) HSP90AA1ALOX5BACE1PRKDCNQO1
SCHEMBL17875829 0.93 ALOX5 (0.49) HSP90AA1ALOX5BACE1PRKDCCDC14B
SCHEMBL17875842 0.93 ALOX5 (0.49) HSP90AA1ALOX5BACE1PRKDCCDC14B
SCHEMBL17875850 0.93 PLA2G2A (0.36) HSP90AA1ALOX5BACE1PRKDCPLA2G2A
SCHEMBL17875859 0.93 PLA2G2A (0.36) HSP90AA1ALOX5BACE1PRKDCPLA2G2A
SCHEMBL17875895 0.88 PRKDC (0.41) HSP90AA1ALOX5BACE1PRKDCMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10581000-B2 Condensed cyclic compound and organic light-emitting device including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2020-03-03 US disclosed
US-20160190482-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2016-06-30 US disclosed
US-20160190482-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2016-06-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10581000-B2 Condensed cyclic compound and organic light-emitting device including the same CRY1, CRY2, CCNE2 HSP90AA1 4363/4885ALOX5 3059/4885BACE1 709/4885
US-20160190482-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CRY2, CCNE2 HSP90AA1 4363/4885ALOX5 3059/4885BACE1 709/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.