SCHEMBL17875977

SCHEMBL17875977

O=S1(=O)Cc2cc(-c3cc(-c4ccccc4)nc(-c4ccccc4)c3)ccc2-c2cc(-c3cc(-c4ccccc4)nc(-c4ccccc4)c3)ccc2C1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.39
KMT2A Q03164 4/20 0.39
CYP19A1 P11511 1/20 0.38
TDP2 O95551 2/20 0.38
PARP10 Q53GL7 1/20 0.37
PARP11 Q9NR21 1/20 0.37
MAPT P10636 4/20 0.36
ALDH1A1 P00352 3/20 0.36
HPGD P15428 2/20 0.36
TYRO3 Q06418 1/20 0.35
NTRK2 Q16620 1/20 0.35
CLK4 Q9HAZ1 1/20 0.35
DYRK1B Q9Y463 1/20 0.35
MCL1 Q07820 2/20 0.35
LMNA P02545 2/20 0.34
NPSR1 Q6W5P4 2/20 0.34
KDM4E B2RXH2 2/20 0.34
HSP90AA1 P07900 1/20 0.34
CTRC Q99895 1/20 0.34
DHODH Q02127 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17875961 0.97 CYP19A1 (0.39) MEN1KMT2ACYP19A1TDP2PARP10
SCHEMBL17875975 0.97 CYP19A1 (0.39) MEN1KMT2ACYP19A1TDP2PARP10
SCHEMBL17876013 0.94 MEN1 (0.43) MEN1KMT2ACYP19A1MAPTALDH1A1
SCHEMBL17876011 0.92 CYP19A1 (0.43) MEN1KMT2ACYP19A1TDP2PARP10
SCHEMBL17875965 0.90 CYP19A1 (0.51) CYP19A1TDP2KDM4EDHODH
SCHEMBL17875974 0.90 CYP19A1 (0.51) CYP19A1TDP2KDM4EDHODH
SCHEMBL17875959 0.87 TDP2 (0.45) MEN1KMT2ATDP2PARP10PARP11
SCHEMBL17875979 0.87 PLA2G2A (0.35) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL17875940 0.87 HCRTR1 (0.34) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL17875973 0.87 HCRTR1 (0.34) MEN1KMT2AMAPTALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10581000-B2 Condensed cyclic compound and organic light-emitting device including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2020-03-03 US disclosed
US-20160190482-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2016-06-30 US disclosed
US-20160190482-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2016-06-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10581000-B2 Condensed cyclic compound and organic light-emitting device including the same CRY1, CRY2, CCNE2 MEN1 448/4885KMT2A 1757/4885CYP19A1 167/4885
US-20160190482-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CRY2, CCNE2 MEN1 448/4885KMT2A 1757/4885CYP19A1 167/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.