SCHEMBL17876089

SCHEMBL17876089

c1ccc2c(c1)oc1c(-c3ccc4c(c3)-c3cc(-c5cccc6oc7ccccc7c56)ccc3OCO4)cccc12

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.53
PRKDC P78527 4/20 0.43
NPC1 O15118 4/20 0.41
MAPT P10636 4/20 0.41
RAB9A P51151 4/20 0.41
KDM4E B2RXH2 3/20 0.41
HPGD P15428 3/20 0.41
SMN1; SMN2 Q16637 3/20 0.41
ALDH1A1 P00352 2/20 0.41
TNKS O95271 1/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
GGPS1 O95749 1/20 0.41
MEN1 O00255 4/20 0.39
KMT2A Q03164 4/20 0.39
HTT P42858 2/20 0.39
TP53 P04637 1/20 0.39
ALOX12 P18054 1/20 0.39
CASP1 P29466 1/20 0.39
CASP7 P55210 1/20 0.39
PTGES2 Q9H7Z7 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17876043 0.95 ALOX5 (0.49) ALOX5PRKDCNPC1MAPTRAB9A
SCHEMBL17876026 0.95 ALOX5 (0.49) ALOX5PRKDCNPC1MAPTRAB9A
SCHEMBL17876087 0.94 ALOX5 (0.59) ALOX5PRKDCNPC1MAPTRAB9A
SCHEMBL17876106 0.92 NPC1 (0.47) ALOX5NPC1MAPTRAB9AKDM4E
SCHEMBL17876091 0.90 ALOX5 (0.53) ALOX5PRKDCNPC1MAPTRAB9A
SCHEMBL17876088 0.90 ALOX5 (0.53) ALOX5PRKDCNPC1MAPTRAB9A
SCHEMBL17876028 0.89 ALOX5 (0.54) ALOX5PRKDCNPC1MAPTRAB9A
SCHEMBL17876097 0.89 ALDH1A1 (0.42) ALOX5PRKDCNPC1MAPTRAB9A
SCHEMBL17876101 0.89 MAPT (0.42) ALOX5NPC1MAPTRAB9AKDM4E
SCHEMBL17876053 0.87 NPC1 (0.46) ALOX5NPC1MAPTRAB9AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10581000-B2 Condensed cyclic compound and organic light-emitting device including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2020-03-03 US disclosed
US-20160190482-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2016-06-30 US disclosed
US-20160190482-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2016-06-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10581000-B2 Condensed cyclic compound and organic light-emitting device including the same CRY1, CRY2, CCNE2 ALOX5 3059/4885PRKDC 4858/4885NPC1 2673/4885
US-20160190482-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CRY2, CCNE2 ALOX5 3059/4885PRKDC 4858/4885NPC1 2673/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.