SCHEMBL17876104

SCHEMBL17876104

c1cncc(-c2cc(-c3cccnc3)cc(-c3ccc4c(c3)-c3cc(-c5ccc6oc7ccccc7c6c5)ccc3OCO4)c2)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP11B1 P15538 4/20 0.46
CYP11B2 P19099 4/20 0.46
PDE10A Q9Y233 2/20 0.46
CLK4 Q9HAZ1 2/20 0.44
PGR P06401 1/20 0.41
MAPT P10636 5/20 0.40
NPC1 O15118 2/20 0.40
RAB9A P51151 2/20 0.40
LMNA P02545 1/20 0.40
TP53 P04637 1/20 0.40
POLB P06746 1/20 0.40
CLK1 P49759 1/20 0.39
KDM4E B2RXH2 2/20 0.39
ALDH1A1 P00352 2/20 0.39
TNKS O95271 1/20 0.39
HPGD P15428 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
CYP19A1 P11511 2/20 0.38
NPSR1 Q6W5P4 1/20 0.38
CYP1A2 P05177 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17876044 0.96 CYP11B1 (0.45) CYP11B1CYP11B2PDE10ACLK4PGR
SCHEMBL17876067 0.96 CYP11B1 (0.45) CYP11B1CYP11B2PDE10ACLK4PGR
SCHEMBL17876098 0.93 CYP11B1 (0.46) CYP11B1CYP11B2PDE10ACLK4PGR
SCHEMBL17876034 0.89 CYP11B1 (0.45) CYP11B1CYP11B2PDE10ACLK4PGR
SCHEMBL17876065 0.89 CYP11B1 (0.45) CYP11B1CYP11B2PDE10ACLK4PGR
SCHEMBL17876102 0.88 CYP11B1 (0.43) CYP11B1CYP11B2PDE10ACLK4PGR
SCHEMBL17876092 0.87 ALOX5 (0.46) CYP11B1CYP11B2PDE10ACLK4PGR
SCHEMBL17876103 0.87 MAPT (0.44) PDE10AMAPTNPC1RAB9ALMNA
SCHEMBL17876203 0.85 BACE1 (0.42) CYP11B1CYP11B2CLK4PGRMAPT
SCHEMBL24493203 0.85 PGR (0.53) CYP11B1CYP11B2CLK4PGRMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10581000-B2 Condensed cyclic compound and organic light-emitting device including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2020-03-03 US disclosed
US-20160190482-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2016-06-30 US disclosed
US-20160190482-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2016-06-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10581000-B2 Condensed cyclic compound and organic light-emitting device including the same CRY1, CRY2, CCNE2 CYP11B1 938/4885CYP11B2 1374/4885PDE10A 2881/4885
US-20160190482-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CRY2, CCNE2 CYP11B1 938/4885CYP11B2 1374/4885PDE10A 2881/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.