SCHEMBL17876110

SCHEMBL17876110

c1ccc(-c2cc(-c3ccccc3)cc(-c3ccc4c(c3)-c3cc(-c5cc(-c6ccccc6)cc(-c6ccccc6)c5)ccc3OCO4)c2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPRC P08575 1/20 0.50
PTGS2 P35354 1/20 0.47
MEN1 O00255 5/20 0.44
KMT2A Q03164 5/20 0.44
NPC1 O15118 4/20 0.44
RAB9A P51151 4/20 0.44
SMN1; SMN2 Q16637 4/20 0.44
ADORA1 P30542 3/20 0.44
PKM P14618 2/20 0.44
ADORA2A P29274 2/20 0.44
ADORA3 P0DMS8 1/20 0.44
MAPT P10636 3/20 0.43
POLB P06746 2/20 0.43
KDM4E B2RXH2 2/20 0.43
ABCG2 Q9UNQ0 1/20 0.43
TSHR P16473 1/20 0.42
L3MBTL1 Q9Y468 2/20 0.41
ALDH1A1 P00352 1/20 0.41
PGR P06401 1/20 0.41
CA12 O43570 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17876062 0.93 PTPRC (0.53) PTPRCPTGS2MEN1KMT2ANPC1
SCHEMBL17876111 0.89 ADORA1 (0.54) PTPRCMEN1KMT2ANPC1RAB9A
SCHEMBL17876109 0.86 CYP11B1 (0.56) NPC1RAB9AMAPTPOLBALDH1A1
SCHEMBL11884874 0.85 PTPRC (0.55) PTPRCPTGS2MEN1KMT2ANPC1
SCHEMBL17876113 0.84 ADORA1 (0.56) PTPRCPTGS2MEN1KMT2ANPC1
SCHEMBL17876096 0.84 ALDH1A1 (0.44) PTPRCMEN1KMT2ANPC1RAB9A
SCHEMBL17876103 0.84 MAPT (0.44) PTPRCPTGS2MEN1KMT2ANPC1
SCHEMBL17876063 0.84 ADORA1 (0.52) PTPRCMEN1KMT2ANPC1RAB9A
SCHEMBL17876075 0.84 ADORA1 (0.52) PTPRCMEN1KMT2ANPC1RAB9A
SCHEMBL404584 0.82 PTGS2 (0.66) PTPRCPTGS2MEN1KMT2ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10581000-B2 Condensed cyclic compound and organic light-emitting device including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2020-03-03 US disclosed
US-20160190482-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2016-06-30 US disclosed
US-20160190482-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2016-06-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10581000-B2 Condensed cyclic compound and organic light-emitting device including the same CRY1, CRY2, CCNE2 PTPRC 4371/4885PTGS2 2749/4885MEN1 448/4885
US-20160190482-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CRY2, CCNE2 PTPRC 4371/4885PTGS2 2749/4885MEN1 448/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.