SCHEMBL17876123

SCHEMBL17876123

CC1(C)Oc2cc(-n3c4ccccc4c4cc(C#N)ccc43)ccc2-c2cc(-c3cc(-c4cccnc4)cc(-c4cccnc4)c3)ccc2O1

nearest known ligand 0.40

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
FLT3 P36888 2/20 0.40
CYP11B2 P19099 8/20 0.39
CYP11B1 P15538 5/20 0.39
CYP17A1 P05093 1/20 0.39
CYP19A1 P11511 1/20 0.35
TNKS O95271 2/20 0.33
BACE1 P56817 2/20 0.33
KCNH2 Q12809 1/20 0.33
STK10 O94804 2/20 0.33
SLK Q9H2G2 2/20 0.33
CHRNB2 P17787 1/20 0.32
CHRNA5 P30532 1/20 0.32
CHRNA4 P43681 1/20 0.32
CTSD P07339 1/20 0.31
MAPK1 P28482 1/20 0.31
NEK1 Q96PY6 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17877827 0.97 CYP11B2 (0.39) FLT3CYP11B2CYP11B1CYP17A1CYP19A1
SCHEMBL17877830 0.96 CYP11B2 (0.41) FLT3CYP11B2CYP11B1CYP17A1CYP19A1
SCHEMBL17876120 0.91 BACE1 (0.38) FLT3CYP11B2CYP11B1CYP17A1CYP19A1
SCHEMBL17877896 0.87 EDNRA (0.33) BACE1CTSD
SCHEMBL17876160 0.87 BACE1 (0.38) CYP11B2CYP11B1CYP17A1CYP19A1TNKS
SCHEMBL17876023 0.87 FLT3 (0.41) FLT3CYP11B2CYP11B1CYP17A1CYP19A1
SCHEMBL17876125 0.87 MYC (0.37) FLT3BACE1SLKCTSD
SCHEMBL17876217 0.87 FLT3 (0.36) FLT3CYP11B2CYP11B1CYP19A1
SCHEMBL17877831 0.86 ABCC9 (0.33) TNKS
SCHEMBL17876185 0.86 BACE1 (0.40) CYP11B2CYP11B1CYP17A1CYP19A1TNKS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10581000-B2 Condensed cyclic compound and organic light-emitting device including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2020-03-03 US disclosed
US-20160190482-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2016-06-30 US disclosed
US-20160190482-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2016-06-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10581000-B2 Condensed cyclic compound and organic light-emitting device including the same CRY1, CRY2, CCNE2 FLT3 2778/4885CYP11B2 1374/4885CYP11B1 938/4885
US-20160190482-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CRY2, CCNE2 FLT3 2778/4885CYP11B2 1374/4885CYP11B1 938/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.