SCHEMBL17876136

SCHEMBL17876136

CC1(C)Oc2cc(-c3ccc4c(c3)oc3ccccc34)ccc2-c2cc(-c3cccc4oc5ccccc5c34)ccc2O1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.36
HCRTR1 O43613 2/20 0.35
AHR P35869 2/20 0.34
PRKDC P78527 1/20 0.34
MEN1 O00255 4/20 0.33
KMT2A Q03164 4/20 0.33
MAPT P10636 2/20 0.33
KDM4E B2RXH2 2/20 0.33
ALDH1A1 P00352 2/20 0.33
HPGD P15428 2/20 0.33
PGR P06401 1/20 0.33
MMP12 P39900 1/20 0.32
MMP13 P45452 1/20 0.32
L3MBTL1 Q9Y468 2/20 0.32
NPC1 O15118 3/20 0.31
RAB9A P51151 3/20 0.31
CASP3 P42574 1/20 0.31
SENP8 Q96LD8 1/20 0.31
SENP7 Q9BQF6 1/20 0.31
SENP6 Q9GZR1 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17876144 1.00 ALOX5 (0.36) ALOX5HCRTR1AHRPRKDCMEN1
SCHEMBL17876199 0.95 ALOX5 (0.39) ALOX5HCRTR1AHRPRKDCMEN1
SCHEMBL17876149 0.95 ALOX5 (0.39) ALOX5AHRMEN1KMT2AMAPT
SCHEMBL17876147 0.93 HSP90AA1 (0.36) ALOX5AHRMEN1KMT2AMAPT
SCHEMBL17876142 0.93 HSP90AA1 (0.36) ALOX5AHRMEN1KMT2AMAPT
SCHEMBL17876134 0.92 AHR (0.40) ALOX5HCRTR1AHRMEN1KMT2A
SCHEMBL17876148 0.91 PLA2G2A (0.35) ALOX5MEN1KMT2AMAPTPGR
SCHEMBL17876170 0.91 PLA2G2A (0.35) ALOX5MEN1KMT2AMAPTPGR
SCHEMBL17876207 0.91 ALOX5 (0.42) ALOX5AHRMEN1KMT2AMAPT
SCHEMBL17876145 0.90 ALOX5 (0.48) ALOX5HCRTR1AHRPRKDCMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10581000-B2 Condensed cyclic compound and organic light-emitting device including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2020-03-03 US disclosed
US-20160190482-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2016-06-30 US disclosed
US-20160190482-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2016-06-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10581000-B2 Condensed cyclic compound and organic light-emitting device including the same CRY1, CRY2, CCNE2 ALOX5 3059/4885HCRTR1 214/4885AHR 1877/4885
US-20160190482-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CRY2, CCNE2 ALOX5 3059/4885HCRTR1 214/4885AHR 1877/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.