SCHEMBL17876157

SCHEMBL17876157

CC1(C)Oc2cc(-c3cc(-c4ccccc4)cc(-c4ccccc4)c3)ccc2-c2cc(-c3cccc4c3oc3ccccc34)ccc2O1

nearest known ligand 0.47

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.47
GGPS1 O95749 1/20 0.39
PRKDC P78527 6/20 0.37
PTGES2 Q9H7Z7 1/20 0.37
PLA2G2A P14555 3/20 0.35
PLA2G4A P47712 3/20 0.35
MEN1 O00255 1/20 0.34
CYP2C19 P33261 1/20 0.34
KMT2A Q03164 1/20 0.34
PLA2G10 O15496 1/20 0.33
AVPR1A P37288 1/20 0.33
PRMT5 O14744 1/20 0.33
WDR77 Q9BQA1 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.32
PGR P06401 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17876143 1.00 ALOX5 (0.47) ALOX5GGPS1PRKDCPTGES2PLA2G2A
SCHEMBL17876192 0.96 ALOX5 (0.51) ALOX5GGPS1PRKDCPTGES2PLA2G2A
SCHEMBL17876127 0.93 ALOX5 (0.53) ALOX5GGPS1PRKDCPTGES2MEN1
SCHEMBL17876132 0.91 ALOX5 (0.43) ALOX5GGPS1PRKDCPTGES2MEN1
SCHEMBL17876166 0.91 ALOX5 (0.43) ALOX5GGPS1PRKDCPTGES2MEN1
SCHEMBL17876145 0.90 ALOX5 (0.48) ALOX5GGPS1PRKDCPTGES2MEN1
SCHEMBL17876137 0.90 ALOX5 (0.48) ALOX5GGPS1PRKDCPTGES2PLA2G2A
SCHEMBL17876126 0.90 ALOX5 (0.48) ALOX5GGPS1PRKDCPTGES2PLA2G2A
SCHEMBL17876128 0.90 ALOX5 (0.48) ALOX5GGPS1PRKDCPTGES2MEN1
SCHEMBL17876148 0.89 PLA2G2A (0.35) ALOX5PLA2G2APLA2G4AMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10581000-B2 Condensed cyclic compound and organic light-emitting device including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2020-03-03 US disclosed
US-20160190482-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2016-06-30 US disclosed
US-20160190482-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2016-06-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10581000-B2 Condensed cyclic compound and organic light-emitting device including the same CRY1, CRY2, CCNE2 ALOX5 3059/4885GGPS1 1622/4885PRKDC 4858/4885
US-20160190482-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CRY2, CCNE2 ALOX5 3059/4885GGPS1 1622/4885PRKDC 4858/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.