SCHEMBL17876183

SCHEMBL17876183

CC1(C)Oc2ccc(-c3cc(-c4ccccc4)cc(-c4ccccc4)c3)cc2-c2cc(-n3c4ccccc4c4ccccc43)ccc2O1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.37
KDM4E B2RXH2 1/20 0.37
ATM Q13315 1/20 0.37
EDNRA P25101 2/20 0.36
EDNRB P24530 1/20 0.36
PGR P06401 2/20 0.34
HSD11B1 P28845 2/20 0.33
HDAC4 P56524 1/20 0.33
KIF11 P52732 1/20 0.32
AKR1C4 P17516 1/20 0.32
AKR1C3 P42330 1/20 0.32
AKR1C2 P52895 1/20 0.32
AKR1C1 Q04828 1/20 0.32
MDM2 Q00987 1/20 0.31
TSPO P30536 1/20 0.31
HTR7 P34969 1/20 0.31
HTR2B P41595 1/20 0.31
TMEM97 Q5BJF2 1/20 0.31
SIGMAR1 Q99720 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17876151 0.94 EDNRA (0.36) L3MBTL1KDM4EATMEDNRAEDNRB
SCHEMBL17876121 0.94 EDNRA (0.36) L3MBTL1KDM4EATMEDNRAEDNRB
SCHEMBL17876216 0.91 MAPK14 (0.32) L3MBTL1KDM4EATMEDNRAEDNRB
SCHEMBL17876186 0.90 MAPT (0.35) L3MBTL1KDM4EATMEDNRAEDNRB
SCHEMBL17877831 0.89 ABCC9 (0.33) EDNRAEDNRBPGR
SCHEMBL17876180 0.88 L3MBTL1 (0.43) L3MBTL1KDM4EATMEDNRAEDNRB
SCHEMBL17876185 0.88 BACE1 (0.40) PGRGSK3BMAPT
SCHEMBL17876164 0.85 KDM4E (0.34) L3MBTL1KDM4EATMEDNRAEDNRB
SCHEMBL17876119 0.85 KDM4E (0.34) L3MBTL1KDM4EATMEDNRAEDNRB
SCHEMBL17876184 0.85 AHR (0.34) L3MBTL1KDM4EATMEDNRAEDNRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10581000-B2 Condensed cyclic compound and organic light-emitting device including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2020-03-03 US disclosed
US-20160190482-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2016-06-30 US disclosed
US-20160190482-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2016-06-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10581000-B2 Condensed cyclic compound and organic light-emitting device including the same CRY1, CRY2, CCNE2 L3MBTL1 768/4885KDM4E 3120/4885ATM 1164/4885
US-20160190482-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CRY2, CCNE2 L3MBTL1 768/4885KDM4E 3120/4885ATM 1164/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.