SCHEMBL17876198

SCHEMBL17876198

CC1(C)Oc2ccc(-c3cc(-c4cccnc4)cc(-c4cccnc4)c3)cc2-c2cc(-c3ccc4c(c3)oc3ccccc34)ccc2O1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 2/20 0.42
KCNH2 Q12809 1/20 0.42
CYP19A1 P11511 4/20 0.40
CYP11B1 P15538 7/20 0.40
CYP11B2 P19099 6/20 0.40
MAPT P10636 3/20 0.39
KDM4E B2RXH2 2/20 0.39
NPC1 O15118 2/20 0.39
RAB9A P51151 2/20 0.39
ALDH1A1 P00352 2/20 0.39
HSD17B10 Q99714 2/20 0.39
HPGD P15428 1/20 0.39
PGR P06401 1/20 0.38
CYP17A1 P05093 1/20 0.37
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
CTSD P07339 1/20 0.35
PIM1 P11309 2/20 0.35
PIM2 Q9P1W9 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17876168 0.96 BACE1 (0.39) BACE1KCNH2CYP19A1CYP11B1CYP11B2
SCHEMBL17876135 0.96 BACE1 (0.39) BACE1KCNH2CYP19A1CYP11B1CYP11B2
SCHEMBL17876203 0.93 BACE1 (0.42) BACE1KCNH2CYP19A1CYP11B1CYP11B2
SCHEMBL17876206 0.89 BACE1 (0.44) BACE1KCNH2CYP19A1CYP11B1CYP11B2
SCHEMBL17876167 0.89 BACE1 (0.39) BACE1KCNH2CYP19A1CYP11B1CYP11B2
SCHEMBL17876155 0.89 BACE1 (0.39) BACE1KCNH2CYP19A1CYP11B1CYP11B2
SCHEMBL17876193 0.87 ALOX5 (0.45) BACE1KCNH2CYP19A1CYP11B1CYP11B2
SCHEMBL17876200 0.87 MMP12 (0.40) CYP19A1MAPTKDM4ENPC1RAB9A
SCHEMBL17876213 0.87 CYP11B1 (0.50) BACE1KCNH2CYP19A1CYP11B1CYP11B2
SCHEMBL17876171 0.86 BACE1 (0.41) BACE1KCNH2CYP19A1CYP11B1CYP11B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10581000-B2 Condensed cyclic compound and organic light-emitting device including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2020-03-03 US disclosed
US-20160190482-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2016-06-30 US disclosed
US-20160190482-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2016-06-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10581000-B2 Condensed cyclic compound and organic light-emitting device including the same CRY1, CRY2, CCNE2 BACE1 709/4885KCNH2 2189/4885CYP19A1 167/4885
US-20160190482-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CRY2, CCNE2 BACE1 709/4885KCNH2 2189/4885CYP19A1 167/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.