Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17876377 | 0.86 | KMT2A (0.39) | ALDH1A1POLBKMT2ATDP1 | |
| SCHEMBL17876366 | 0.80 | ALOX15 (0.43) | ALDH1A1POLBKMT2ATDP1ALOX15 | |
| SCHEMBL17876391 | 0.72 | MAPT (0.46) | ALDH1A1POLBKMT2ATDP1ALOX15 | |
| SCHEMBL17876359 | 0.69 | ALDH2 (0.39) | ALDH1A1POLBKMT2ATDP1ALDH2 | |
| SCHEMBL17876389 | 0.67 | ALDH1A1 (0.38) | ALDH1A1POLBKMT2ATDP1 | |
| SCHEMBL26035377 | 0.63 | ALOX15 (0.34) | ALDH1A1POLBKMT2ATDP1ALDH2 | |
| SCHEMBL16803424 | 0.63 | NR1H3 (0.33) | — | |
| SCHEMBL26035381 | 0.62 | ALOX15 (0.33) | ALDH1A1POLBKMT2ATDP1ALDH2 | |
| SCHEMBL17876374 | 0.59 | ALOX15 (0.39) | ALDH1A1POLBKMT2ATDP1ALOX15 | |
| SCHEMBL12430910 | 0.58 | FFAR1 (0.45) | ALDH1A1TDP1HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160185745-A1 | ANALOGS OF VINAXANTHONE AND XANTHOFULVIN, METHODS OF SYNTHESIS, AND METHODS OF TREATMENTS THEREOF | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2016-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160185745-A1 | ANALOGS OF VINAXANTHONE AND XANTHOFULVIN, METHODS OF SYNTHESIS, AND METHODS OF TREATMENTS THEREOF | VAT1, NQO1, VARS1 | ALDH1A1 2380/4885POLB 1216/4885KMT2A 2453/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.