Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | ACHE | P22303 | 2/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL575883 | 0.84 | HDAC7 (0.46) | HDAC7PSMB5PTGDR2MAOBELANE | |
| SCHEMBL576376 | 0.84 | HDAC7 (0.46) | HDAC7PSMB5PTGDR2MAOBELANE | |
| SCHEMBL9914232 | 0.82 | HDAC7 (0.45) | HDAC7PSMB5PTGDR2MAOBELANE | |
| SCHEMBL13750090 | 0.79 | HTR1A (0.47) | HDAC7PSMB5PTGDR2MAOBELANE | |
| SCHEMBL28223280 | 0.79 | PTGDR2 (0.44) | HDAC7PSMB5PTGDR2MAOBELANE | |
| SCHEMBL25811691 | 0.78 | MAPT (0.43) | HDAC7PSMB5PTGDR2KDM4EALDH1A1 | |
| SCHEMBL1784382 | 0.77 | MAPT (0.43) | PSMB5ALDH1A1L3MBTL1LMNAMAPT | |
| SCHEMBL16678768 | 0.75 | ACHE (0.50) | MAOBALDH1A1LMNAMAPTTSHR | |
| SCHEMBL3005820 | 0.74 | ELANE (0.52) | HDAC7PSMB5PTGDR2MAOBELANE | |
| SCHEMBL6893252 | 0.74 | HTR7 (0.47) | KDM4EALDH1A1LMNAMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2323975-B1 | MULTI-RING ANTIOXIDANTS WITH ANTIWEAR PROPERTIES | SI GROUP INC (US) | 2019-04-24 | — | — | EP | disclosed |
| US-9796939-B2 | Multi-ring antioxidants with antiwear properties | SI GROUP, INC. (US) | 2017-10-24 | — | — | US | disclosed |
| US-20140038871-A1 | MULTI-RING ANTIOXIDANTS WITH ANTIWEAR PROPERTIES | ALBEMARLE CORPORATION (US) | 2014-02-06 | — | — | US | disclosed |
| US-8580718-B2 | Multi-ring antioxidants with antiwear properties | ALBERMARLE CORPORATION (US) | 2013-11-12 | — | — | US | disclosed |
| US-20110124540-A1 | MULTI-RING ANTIOXIDANTS WITH ANTIWEAR PROPERTIES | ALBEMARLE CORPORATION (US) | 2011-05-26 | — | — | US | disclosed |
| EP-2323975-A2 | MULTI-RING ANTIOXIDANTS WITH ANTIWEAR PROPERTIES | Albemarle Corporation (US) | 2011-05-25 | — | — | EP | disclosed |
| WO-2010011523-A2 | MULTI-RING ANTIOXIDANTS WITH ANTIWEAR PROPERTIES | ALBEMARLE CORPORATION (US) | 2010-01-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110124540-A1 | MULTI-RING ANTIOXIDANTS WITH ANTIWEAR PROPERTIES | GSR, CBR1, SOD1 | HDAC7 4150/4885PSMB5 2779/4885PTGDR2 2935/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.