SCHEMBL17877638

SCHEMBL17877638

CC(=O)ON=C(c1ccc2c(c1)C(C)(C)c1cc(Cl)ccc1-2)c1ccccc1C

nearest known ligand 0.37

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ MAP2 P11137 1/20 0.36
▸ ALDH1A1 P00352 2/20 0.35
▸ KCNMA1 Q12791 1/20 0.35
▸ HPGD P15428 3/20 0.35
▸ KMT2A Q03164 2/20 0.35
▸ MEN1 O00255 1/20 0.35
▸ NPC1 O15118 5/20 0.34
▸ RAB9A P51151 5/20 0.34
▸ POLB P06746 1/20 0.34
▸ HTR7 P34969 1/20 0.34
▸ HTR2B P41595 1/20 0.34
▸ MAPT P10636 3/20 0.33
▸ SMN1; SMN2 Q16637 3/20 0.33
▸ RXRA P19793 1/20 0.33
▸ RXRB P28702 1/20 0.33
▸ RXRG P48443 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17877635 0.89 MAP2 (0.35) MAP2ALDH1A1KCNMA1HPGDKMT2A
SCHEMBL17877629 0.87 MAP2 (0.34) MAP2ALDH1A1KCNMA1HPGDKMT2A
SCHEMBL18924209 0.85 NPC1 (0.48) ALDH1A1HPGDKMT2AMEN1NPC1
SCHEMBL19186763 0.83 KMT2A (0.46) MAP2ALDH1A1KCNMA1HPGDKMT2A
SCHEMBL18852824 0.79 ALDH1A1 (0.39) ALDH1A1HPGDKMT2AMEN1NPC1
SCHEMBL18012772 0.79 RXRA (0.42) ALDH1A1KMT2AMEN1POLBMAPT
SCHEMBL19307923 0.76 ALDH1A1 (0.37) ALDH1A1HPGDKMT2ANPC1RAB9A
SCHEMBL18933437 0.75 NPC1 (0.34) ALDH1A1HPGDKMT2ANPC1RAB9A
SCHEMBL18218064 0.74 NPC1 (0.44) ALDH1A1HPGDKMT2AMEN1NPC1
SCHEMBL23552654 0.73 RAB9A (0.33) ALDH1A1KMT2ANPC1RAB9APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10351526-B2 Coloring curable resin composition, cured film, color filter, method for manufacturing color filter, solid-state imaging device, image display device, compound, and cation FUJIFILM CORPORATION (JP) 2019-07-16 — — US disclosed
US-9720319-B2 Colored composition, cured film, color filter, method for manufacturing color filter, solid-state imaging element, image display device, and compound FUJIFILM CORPORATION (JP) 2017-08-01 — — US disclosed
US-9720319-B2 Colored composition, cured film, color filter, method for manufacturing color filter, solid-state imaging element, image display device, and compound FUJIFILM CORPORATION (JP) 2017-08-01 — — US disclosed
US-9605154-B2 Curable coloring composition, cured film, color filter, method for manufacturing color filter, solid-state image pickup element, picture display device, and triarylmethane compound FUJIFILM CORPORATION (JP) 2017-03-28 — — US disclosed
US-9605154-B2 Curable coloring composition, cured film, color filter, method for manufacturing color filter, solid-state image pickup element, picture display device, and triarylmethane compound FUJIFILM CORPORATION (JP) 2017-03-28 — — US disclosed
US-20160216604-A1 COLORED COMPOSITION, CURED FILM, COLOR FILTER, METHOD FOR MANUFACTURING COLOR FILTER, SOLID-STATE IMAGING ELEMENT, IMAGE DISPLAY DEVICE, AND COMPOUND FUJIFILM CORPORATION (JP) 2016-07-28 — — US disclosed
US-20160185969-A1 CURABLE COLORING COMPOSITION, CURED FILM, COLOR FILTER, METHOD FOR MANUFACTURING COLOR FILTER, SOLID-STATE IMAGE PICKUP ELEMENT, PICTURE DISPLAY DEVICE, AND TRIARYLMETHANE COMPOUND FUJIFILM CORPORATION (JP) 2016-06-30 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10351526-B2 Coloring curable resin composition, cured film, color filter, method for manufacturing color filter, solid-state imaging device, image display device, compound, and cation O60361, WDR12, SEM1 MAP2 2130/4885ALDH1A1 2079/4885KCNMA1 1335/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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