SCHEMBL178788

SCHEMBL178788

O=C(NC(C(=O)O)C1CCCCC1)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.50

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MDM4 O15151 2/20 0.48
TP53 P04637 2/20 0.48
CASP3 P42574 3/20 0.48
KMT2A Q03164 2/20 0.48
EPHX2 P34913 1/20 0.46
TLR2 O60603 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10231780 1.00 MDM4 (0.48) MDM4TP53CASP3KMT2AEPHX2
SCHEMBL29399489 1.00 MDM4 (0.48) MDM4TP53CASP3KMT2AEPHX2
SCHEMBL20825662 1.00 MDM4 (0.48) MDM4TP53CASP3KMT2AEPHX2
SCHEMBL178780 1.00 MDM4 (0.48) MDM4TP53CASP3KMT2AEPHX2
SCHEMBL1405653 1.00 MDM4 (0.48) MDM4TP53CASP3KMT2AEPHX2
SCHEMBL13697519 1.00 MDM4 (0.48) MDM4TP53CASP3KMT2AEPHX2
SCHEMBL29398335 1.00 MDM4 (0.48) MDM4TP53CASP3KMT2AEPHX2
SCHEMBL178777 0.99 CASP3 (0.49) MDM4TP53CASP3KMT2AEPHX2
SCHEMBL17256393 0.99 CASP3 (0.49) MDM4TP53CASP3KMT2AEPHX2
SCHEMBL30291644 0.99 CASP3 (0.49) MDM4TP53CASP3KMT2AEPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4748847-A1 PEPTIDE COMPLEX HAVING VEGFR -2 AGONIST ACTIVITY Peptidream Inc (JP) 2026-05-27 EP disclosed
US-20260098061-A1 EPHA2-BINDING PENDING PEPTIDE AND COMPOSITION COMPRISING SAME PEPTIDREAM INC (JP) 2026-04-09 US disclosed
US-20260036595-A1 STRUCTURE-BASED PEPTIDES FOR DETECTION OF TRANSTHYRETIN AMYLOID FIBRILS AND AGGREGATES IN PREECLAMPSIA THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2026-02-05 US disclosed
EP-3966226-B1 MASP INHIBITORY COMPOUNDS AND USES THEREOF BAYER AG (DE) 2025-12-24 EP disclosed
US-12503491-B2 MASP inhibitory compounds and uses thereof BAYER AKTIENGESELLSCHAFT (DE) 2025-12-23 US disclosed
US-20250362310-A1 STRUCTURE-BASED PROBE FOR DETECTION OF TRANSTHYRETIN AMYLOID FIBRILS AND AGGREGATES THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2025-11-27 US disclosed
EP-4594337-A2 RADIOPHARMACEUTICAL COMPOSITIONS TARGETING EPHRIN TYPE-A RECEPTOR 2 AND USES THEREOF Rayzebio, Inc. (US) 2025-08-06 EP disclosed
US-12371454-B2 Cyclic peptide compound having Kras inhibitory action CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2025-07-29 US disclosed
US-20240400617-A1 CYCLIC PEPTIDE COMPOUND HAVING KRAS INHIBITORY ACTION CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2024-12-05 US disclosed
US-20240148821-A1 PHARMACEUTICAL USE OF CYCLIC PEPTIDE COMPOUND CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2024-05-09 US disclosed
EP-1641795-B1 TRIAZA- AND TETRAAZA-ANTHRACENEDIONE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS PHARMACEUTICALS SANOFI AVENTIS DEUTSCHLAND (DE) 2011-03-09 EP disclosed
US-7132536-B2 Triaza- and tetraaza-anthracenedione derivatives, their preparation and their use as pharmaceuticals SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) 2006-11-07 US disclosed
EP-1641795-A1 TRIAZA- AND TETRAAZA-ANTHRACENEDIONE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS PHARMACEUTICALS Sanofi-Aventis Deutschland GmbH (DE) 2006-04-05 EP disclosed
US-20040248900-A1 Triaza- and tetraaza-anthracenedione derivatives, their preparation and their use as pharmaceuticals AVENTIS PHARMA DEUTSCHLAND GMBH (DE) 2004-12-09 US disclosed
WO-2004094425-A1 Triaza- and tetraaza-anthracenedione derivatives, their preparation and their use as pharmaceuticals SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) 2004-11-04 WO disclosed
EP-1471066-A1 Triaza- and tetraaza-anthracenedione derivates, their preparation and their use as pharmaceuticals Aventis Pharma Deutschland GmbH (DE) 2004-10-27 EP disclosed
CN-1406226-A Novel malonic acid derivatives, process for their preparation, their use as inhibitors of factor XA activity and pharmaceutical compositions containing them AVENTIS PHARMA GMBH (DE) 2003-03-26 CN disclosed
CN-1332723-A Arylalkanoyl derivatives, processes for their preparation, their use and pharmaceutical compositions containing them AVENTIS PHARMA GMBH (DE) 2002-01-23 CN disclosed
EP-1150946-A1 ARYLALKANOYL DERIVATIVES, PROCESSES FOR THEIR PREPARATION, THEIR USE AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM Aventis Pharma Deutschland GmbH (DE) 2001-11-07 EP disclosed
WO-2000040548-A1 ARYLALKANOYL DERIVATIVES, PROCESSES FOR THEIR PREPARATION, THEIR USE AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AVENTIS PHARMA DEUTSCHLAND GMBH (DE) 2000-07-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12503491-B2 MASP inhibitory compounds and uses thereof MASP2, SERPINB1, SPINT2 MDM4 2629/4885TP53 2648/4885CASP3 795/4885
US-20240400617-A1 CYCLIC PEPTIDE COMPOUND HAVING KRAS INHIBITORY ACTION KRAS, NRAS, HRAS MDM4 441/4885TP53 34/4885CASP3 3906/4885
US-20040248900-A1 Triaza- and tetraaza-anthracenedione derivatives, their preparation and their use as pharmaceuticals CYP19A1, TBXAS1, CYP11B1 MDM4 3885/4885TP53 3837/4885CASP3 2044/4885
US-20240148821-A1 PHARMACEUTICAL USE OF CYCLIC PEPTIDE COMPOUND VIP, IAPP, KRAS MDM4 1294/4885TP53 178/4885CASP3 3268/4885
US-20260098061-A1 EPHA2-BINDING PENDING PEPTIDE AND COMPOSITION COMPRISING SAME EPHA2, EPHA1, EPHB1 MDM4 1959/4885TP53 412/4885CASP3 4663/4885
US-12371454-B2 Cyclic peptide compound having Kras inhibitory action KRAS, NRAS, HRAS MDM4 441/4885TP53 34/4885CASP3 3906/4885
US-20260036595-A1 STRUCTURE-BASED PEPTIDES FOR DETECTION OF TRANSTHYRETIN AMYLOID FIBRILS AND AGGREGATES IN PREECLAMPSIA TTR, APP, SERPINA3 MDM4 2595/4885TP53 940/4885CASP3 609/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.