SCHEMBL17879352

SCHEMBL17879352

c1ccc(-c2nnc(-c3ccc(N4c5ccccc5N(c5ccccc5)c5ccccc54)cc3)o2)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 14/20 0.61
RAB9A P51151 14/20 0.61
SMN1; SMN2 Q16637 8/20 0.61
HPGD P15428 6/20 0.55
NFKB1 P19838 2/20 0.55
NFKB2 Q00653 2/20 0.55
RELA Q04206 2/20 0.55
POLB P06746 1/20 0.55
MEN1 O00255 1/20 0.55
KMT2A Q03164 1/20 0.55
ALDH1A1 P00352 5/20 0.53
KDM4E B2RXH2 4/20 0.53
HSD17B10 Q99714 2/20 0.53
GLA P06280 1/20 0.53
MAPT P10636 1/20 0.53
ALOX15 P16050 1/20 0.53
ATAD2 Q6PL18 1/20 0.52
GAA P10253 1/20 0.51
PTGS2 P35354 1/20 0.49
CA1 P00915 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17879367 0.98 NPC1 (0.57) NPC1RAB9ASMN1; SMN2HPGDNFKB1
SCHEMBL13427099 0.92 RAB9A (0.53) NPC1RAB9ASMN1; SMN2HPGDNFKB1
SCHEMBL23085200 0.88 NPC1 (0.47) NPC1RAB9ASMN1; SMN2HPGDNFKB1
SCHEMBL21450005 0.87 SMN1; SMN2 (0.70) NPC1RAB9ASMN1; SMN2HPGDNFKB1
SCHEMBL17879333 0.87 NPC1 (0.53) NPC1RAB9ASMN1; SMN2HPGDNFKB1
SCHEMBL17879336 0.85 HPGD (0.52) NPC1RAB9ASMN1; SMN2HPGDNFKB1
SCHEMBL17879351 0.84 NPC1 (0.50) NPC1RAB9ASMN1; SMN2HPGDNFKB1
SCHEMBL18884735 0.84 AVPR1A (0.43) NPC1RAB9ASMN1; SMN2HPGDNFKB1
SCHEMBL22417901 0.83 NPC1 (0.49) NPC1RAB9ASMN1; SMN2HPGDNFKB1
SCHEMBL22417786 0.83 NPC1 (0.49) NPC1RAB9ASMN1; SMN2HPGDNFKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11820761-B2 Organic compound, organic light emitting diode and organic light emitting device including the organic compound LG DISPLAY CO., LTD. (KR) 2023-11-21 US disclosed
US-20230365857-A1 ORGANIC MIXTURES AND APPLICATIONS THEREOF IN ORGANIC ELECTRONIC DEVICES Zhejiang Brilliant Optoelectronic Technology Co.,Ltd. (CN) 2023-11-16 US disclosed
US-20230365857-A1 ORGANIC MIXTURES AND APPLICATIONS THEREOF IN ORGANIC ELECTRONIC DEVICES Zhejiang Brilliant Optoelectronic Technology Co.,Ltd. (CN) 2023-11-16 US disclosed
US-20230363257-A1 ORGANIC MIXTURES AND APPLICATIONS THEREOF IN ORGANIC ELECTRONIC DEVICES Zhejiang Brilliant Optoelectronic Technology Co.,Ltd. (CN) 2023-11-09 US disclosed
US-20230363257-A1 ORGANIC MIXTURES AND APPLICATIONS THEREOF IN ORGANIC ELECTRONIC DEVICES Zhejiang Brilliant Optoelectronic Technology Co.,Ltd. (CN) 2023-11-09 US disclosed
WO-2023124164-A1 ORGANIC ELECTROLUMINESCENT DEVICE AND DISPLAY DEVICE 昆山国显光电有限公司 2023-07-06 WO disclosed
EP-3790068-B1 ORGANIC COMPOUND, ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DEVICE INCLUDING THE ORGANIC COMPOUND LG DISPLAY CO LTD (KR) 2023-07-05 EP disclosed
US-11512039-B2 Aromatic amine derivatives, preparation methods therefor, and uses thereof GUANGZHOU CHINARAY OPTOELECTRONIC MATERIALS LTD. (CN) 2022-11-29 US disclosed
US-11508927-B2 Organic electroluminescence device, preparation method thereof and display apparatus KUNSHAN GO-VISIONOX OPTO-ELECTRONICS CO., LTD (CN) 2022-11-22 US disclosed
US-20220149281-A1 ORGANIC ELECTROLUMINESCENT DEVICE, DISPLAY PANEL AND DISPLAY DEVICE KUNSHAN GO-VISIONOX OPTO-ELECTRONICS CO., LTD (CN) 2022-05-12 US disclosed
US-20170263869-A1 ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2017-09-14 US disclosed
US-20170213974-A1 ORGANIC LIGHT-EMITTING DEVICE, HOST MATERIAL, LIGHT-EMITTING MATERIAL, AND COMPOUND KYULUX, INC. (JP) 2017-07-27 US disclosed
US-20170213974-A1 ORGANIC LIGHT-EMITTING DEVICE, HOST MATERIAL, LIGHT-EMITTING MATERIAL, AND COMPOUND KYULUX, INC. (JP) 2017-07-27 US disclosed
US-20170163010-A1 ORGANIC LIGHT-EMITTING ELEMENT KYUSHU UNIVERSITY NATIONAL UNIVERSITY CORPORATION (JP) 2017-06-08 US disclosed
US-20170163010-A1 ORGANIC LIGHT-EMITTING ELEMENT KYUSHU UNIVERSITY NATIONAL UNIVERSITY CORPORATION (JP) 2017-06-08 US disclosed
EP-3171421-A1 ORGANIC LIGHT-EMITTING ELEMENT Kyushu University, National University Corporation (JP) 2017-05-24 EP disclosed
US-20170018600-A1 ORGANIC LIGHT-EMITTING DISPLAY DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-01-19 US disclosed
US-20170018600-A1 ORGANIC LIGHT-EMITTING DISPLAY DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-01-19 US disclosed
US-20160190478-A1 ORGANIC ELECTROLUMINESCENT DEVICE KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2016-06-30 US disclosed
US-20160190478-A1 ORGANIC ELECTROLUMINESCENT DEVICE KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2016-06-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230365857-A1 ORGANIC MIXTURES AND APPLICATIONS THEREOF IN ORGANIC ELECTRONIC DEVICES H1-0, OR10J3, H1-2 NPC1 2955/4885RAB9A 3214/4885SMN1; SMN2 3579/4885
US-11512039-B2 Aromatic amine derivatives, preparation methods therefor, and uses thereof SLC7A1, WEE1, SLC7A5 NPC1 2907/4885RAB9A 3519/4885SMN1; SMN2 3350/4885
US-11820761-B2 Organic compound, organic light emitting diode and organic light emitting device including the organic compound OCIAD1, OCIAD2, ORC3 NPC1 845/4885RAB9A 1914/4885SMN1; SMN2 3165/4885
US-20170263869-A1 ORGANIC ELECTROLUMINESCENT ELEMENT VDAC1, VDAC3, ELOC NPC1 3500/4885RAB9A 2084/4885SMN1; SMN2 2912/4885
US-20170213974-A1 ORGANIC LIGHT-EMITTING DEVICE, HOST MATERIAL, LIGHT-EMITTING MATERIAL, AND COMPOUND CRY1, CRY2, CYBA NPC1 3146/4885RAB9A 4082/4885SMN1; SMN2 3376/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.