SCHEMBL17879453

SCHEMBL17879453

CC1(C)c2cc(-c3ccccc3)ccc2N(c2cccc3c2-c2ccccc2C32c3ccccc3-c3ccc4c(oc5ccccc54)c32)c2ccc(-c3ccccc3)cc21

nearest known ligand 0.34

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.34
PRKDC P78527 1/20 0.33
PDK2 Q15119 1/20 0.31
PGR P06401 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19669001 0.87 ALOX5 (0.32) ALOX5PRKDC
SCHEMBL15213627 0.83 PDK2 (0.37) PDK2PGR
SCHEMBL19001836 0.82 PDK2 (0.38) PDK2PGR
SCHEMBL25997489 0.81 PRKDC (0.35) ALOX5PRKDC
SCHEMBL19883133 0.81 ALOX5 (0.32) ALOX5
SCHEMBL17816797 0.81 PDK2 (0.36) PDK2PGR
SCHEMBL16810737 0.81 PDK2 (0.36) PDK2PGR
SCHEMBL19760229 0.81 ALOX5 (0.33) ALOX5PRKDCPDK2
SCHEMBL17879452 0.80 ALOX5 (0.35) ALOX5PRKDC
SCHEMBL19001815 0.80 PDK2 (0.39) PDK2PGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10665790-B2 Materials for electronic devices MERCK PATENT GMBH (DE) 2020-05-26 US disclosed
US-9978950-B2 Materials for electronic devices MERCK PATENT GMBH (DE) 2018-05-22 US disclosed
US-9978950-B2 Materials for electronic devices MERCK PATENT GMBH (DE) 2018-05-22 US disclosed
US-9837617-B2 Materials for electronic devices MERCK PATENT GMBH (DE) 2017-12-05 US disclosed
US-20170301865-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2017-10-19 US disclosed
US-20170301865-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2017-10-19 US disclosed
US-20160190466-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2016-06-30 US disclosed
US-20160190466-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2016-06-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10665790-B2 Materials for electronic devices SDHB, SDHA, ETFB ALOX5 3759/4885PRKDC 4064/4885PDK2 178/4885
US-20160190466-A1 MATERIALS FOR ELECTRONIC DEVICES SDHB, SDHA, ETFB ALOX5 3759/4885PRKDC 4064/4885PDK2 178/4885
US-20170301865-A1 MATERIALS FOR ELECTRONIC DEVICES SDHB, SDHA, ETFB ALOX5 3759/4885PRKDC 4064/4885PDK2 178/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.